Synthesis, biological evaluation, and modeling of a C,D-seco-taxoid
A C,D-seco-paclitaxel derivative 12 was prepared and tested for biological activity. The key step in the synthesis was a free radical fragmentation of the bicyclic tertiary alcohol 7 under the conditions of the hypobromite reaction. The compound 12 showed
Ferjancic, Zorana,Matovic, Radomir,Cekovic, Zivorad,Snyder, James P.,Radomir, N. Saicic
Get Best Price for911285-72-8(2R,4S,5R)-3-Benzoyl-2-(4-methoxy-phenyl)-4-phenyl-oxazolidine-5-carboxylic acid (1S,2S,3R,10R,11R,12R,15S)-11,12-diacetoxy-2-benzoyloxy-1-hydroxy-10,14,17,17-tetramethyl-4-oxo-6-oxa-tricyclo[11.3.1.03,10]heptadec-13-en-15-yl ester