Reaction of Nitriles Under Acidic Conditions. Part III. A Facile Synthesis of Thienopyrimidin-4(3H)-ones
A variety of thiophene o-aminoesters were reacted with cyanates, thiocyanates, cyanamides, acyl cyanides and α-functionalized acetonitrile derivatives to yield the corresponding 2-substituted thienopyrimidin-4(3H)-ones.
Shishoo, C. J.,Devani, M. B.,Pathak, U. S.,Ananthan, S.,Bhadti, V. S.,et al.
p. 375 - 380
(2007/10/02)
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