913388-66-6 Usage
Uses
Used in Organic Synthesis:
1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester is utilized as a key intermediate in organic synthesis for the creation of complex organic molecules. Its unique structure allows for various chemical reactions, facilitating the synthesis of a wide range of compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester is employed as a building block for designing and developing new pharmaceuticals and drug candidates. Its structural features enable the creation of molecules with potential therapeutic properties.
Used as a Ligand in Metal-Catalyzed Cross-Coupling Reactions:
The boronic acid group present in this compound makes it a valuable ligand for metal-catalyzed cross-coupling reactions. These reactions are crucial in the synthesis of various organic compounds, including those with pharmaceutical relevance.
Used in Prodrug Design:
The ester functionality of 1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester may render it suitable for use in prodrug designs. Prodrugs are compounds that are modified to enhance their pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, ultimately improving their therapeutic efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 913388-66-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,3,3,8 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 913388-66:
(8*9)+(7*1)+(6*3)+(5*3)+(4*8)+(3*8)+(2*6)+(1*6)=186
186 % 10 = 6
So 913388-66-6 is a valid CAS Registry Number.
InChI:InChI=1/C18H25BN2O6/c1-17(2,3)26-15(22)20-12-7-8-13-11(9-12)10-14(19(24)25)21(13)16(23)27-18(4,5)6/h7-10,24-25H,1-6H3,(H,20,22)
913388-66-6Relevant articles and documents
INHIBITORS OF HEPATITIS C VIRUS REPLICATION
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, (2019/05/15)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
INHIBITORS OF HEPATITIS C VIRUS REPLICATION
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Page/Page column 98, (2010/11/04)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
JAK INHIBITOR
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Page/Page column 81, (2009/10/21)
A JAK inhibitor comprising, as an active ingredient, a nitrogen-containing heterocyclic compound represented by formula (I) {wherein W represents a nitrogen atom or -CH-; X represents -C (=O) - or -CHR4- (wherein R4 represents a hydrogen atom, or the like); R1 represents the formula described below [wherein Q1 represents-CR8-(wherein R8 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like); Q2 represents -NR15- (wherein R15 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like); and R5 and R6 may be the same or different and each represents a hydrogen atom, halogen, carboxy, substituted or unsubstituted lower alkyl, or the like], or the like; and R2 and R3 may be the same or different and each represents a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, or the like} or a pharmaceutically acceptable salt thereof.
