1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester

Base Information

• Chemical Name: 1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester
• CAS No.: 913388-66-6
• Molecular Formula: C18H25BN2O6
• Molecular Weight: 376.217
• Hs Code.: 2933990090
• Mol file: 913388-66-6.mol

Synonyms:1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester;

Chemical Property of 1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester

Chemical Property:

• PSA: 110.02000
• Density: 1.2g/cm³
• LogP: 2.52430
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(1-(tert-Butoxycarbonyl)-5-((tert-butoxycarbonyl)-amino)-1H-indol-2-yl)boronic acid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester

There total 5 articles about 1H-Indole-1-carboxylic acid, 2-borono-5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

→ (1-(tert-butoxycarbonyl)-5-((tert-butoxycarbonyl)amino)-1H-indol-2-yl)boronic acid (913388-66-6)

Guidance literature:

Reference yield:

5-(tert-butoxycarbonylamino)-1-(tert-butoxycarbonyl)indole (253782-96-6) → (1-(tert-butoxycarbonyl)-5-((tert-butoxycarbonyl)amino)-1H-indol-2-yl)boronic acid (913388-66-6)

Guidance literature:

5-(tert-butoxycarbonylamino)-1-(tert-butoxycarbonyl)indole; With Triisopropyl borate; lithium diisopropyl amide; In tetrahydrofuran; at 0 - 25 ℃; for 2h;

With hydrogenchloride; water; In tetrahydrofuran; pH=3;

Reference yield:

C24H37BN2O6 → (1-(tert-butoxycarbonyl)-5-((tert-butoxycarbonyl)amino)-1H-indol-2-yl)boronic acid (913388-66-6)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; pH=3;

upstream raw materials:

5-amino-1H-indole

5-(tert-butoxycarbonylamino)-1-(tert-butoxycarbonyl)indole

5-nitroindole

Downstream raw materials:

C₃₉H₄₃N₅O₆

C₃₇H₄₁N₅O₆

C₃₈H₄₁N₅O₇