913706-72-6

Basic information

• Product Name: 1-[(3aR,8aR)-tetrahydro-2,2-diMethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-Pyrrolidine
• Synonyms: 1-[(3aR,8aR)-tetrahydro-2,2-diMethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-Pyrrolidine
• CAS NO: 913706-72-6
• Molecular Formula: C35H36NO4P
• Molecular Weight: 565.638401
• Mol File: 913706-72-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-[(3aR,8aR)-tetrahydro-2,2-diMethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-Pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(3aR,8aR)-tetrahydro-2,2-diMethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-Pyrrolidine(913706-72-6)
• EPA Substance Registry System: 1-[(3aR,8aR)-tetrahydro-2,2-diMethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-Pyrrolidine(913706-72-6)

Safety Data

• Hazardous Substances Data: 913706-72-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
1-[(3aR,8aR)-tetrahydro-2,2-diMethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-Pyrrolidine is used as a reagent or precursor in the synthesis of other compounds due to its complex structure and unique functional groups.
Used in Pharmaceutical Industry:
1-[(3aR,8aR)-tetrahydro-2,2-diMethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-Pyrrolidine may be utilized as a building block for the development of new pharmaceuticals, given its potential to form novel molecular structures with therapeutic properties.
Used in Material Science:
In the field of material science, 1-[(3aR,8aR)-tetrahydro-2,2-diMethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]-Pyrrolidine could be employed in the design and synthesis of advanced materials with specific properties, such as improved stability or reactivity.

Upstream product

• 123-75-1 pyrrolidine 
• 299917-90-1 (3aR,8aR)-6-chloro-2,2-dimethyl-4,4,8,8-tetraphenyltetrahydro[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine 
• 93379-48-7 (R,R)-TADDOL 

Relevant articles and documents

Ni-Catalyzed Asymmetric Cycloisomerization of Dienes by Using TADDOL Phosphoramidites

A library of α,α,α,α-tetraaryl-1,3-dioxolane-4,5-dimethanol (TADDOL)-based phosphoramidites has been synthesized and applied in the Ni-catalyzed cycloisomerization of different dienes. Through the systematic variation of the three structural motifs of the

Development, mechanism, and scope of the palladium-catalyzed enantioselective allene diboration

In the presence of a chiral phosphoramidite ligand, the palladium-catalyzed diboration of allenes can be executed with high enantioselectivity. This reaction provides high levels of selectivity with a range of aromatic and aliphatic allene substrates. Iso

Enantioselective rhodium-catalyzed [2+2+2] cycloaddition of alkenyl isocyanates and terminal alkynes: Application to the total synthesis of (+)-lasubine II

The use of TADDOL-based phosphoramidite ligands on rhodium allows for the incorporation of terminal alkynes in the [2+2+2] cycloaddition with alkenyl isocyanates. Terminal aliphatic alkynes provide bicyclic lactams, while the use of aryl alkynes provides complementary access to vinylogous amides. Product selectivity seems to be governed by a combination of electronics and sterics, with smaller and/or more electron-deficient substituents favoring lactam formation. The use of homologous alkenyl isocyanates leads to an expedient asymmetric total synthesis of the alkaloid lasubine II. Copyright