915160-96-2

Basic information

• Product Name: (3,4-Dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol
• Synonyms: (3,4-Dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol;3,4-Dihydro-2H-1,4-Benzoxazin-6-Ylmethanol(WX640269)
• CAS NO: 915160-96-2
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.19
• Mol File: 915160-96-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3,4-Dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3,4-Dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol(915160-96-2)
• EPA Substance Registry System: (3,4-Dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol(915160-96-2)

Safety Data

• Hazardous Substances Data: 915160-96-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
(3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol is used as a building block for the development of various drugs and bioactive molecules. Its structural features and functional groups make it a promising candidate for creating new pharmaceutical compounds.
Used in Organic Synthesis:
(3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol is used as a key intermediate in the synthesis of complex organic molecules. Its versatility and reactivity make it a valuable component in the creation of a wide range of organic compounds.
Used in Materials Science:
(3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-methanol is used as a component in the development of new polymers and advanced materials. Its unique properties and potential applications in materials science make it a valuable resource for creating innovative materials with improved properties.

Upstream product

• 52820-13-0 3-Amino-4-hydroxybenzyl alcohol 
• 106-93-4 ethylene dibromide 
• 200195-15-9 3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbaldehyde 
• 604756-32-3 methyl 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylate 
• 536-25-4 methyl 3-amino-4-hydroxybenzoate 
• 616-82-0 3-nitro-4-hydroxybenzoic acid 
• 99-42-3 methyl (4-hydroxy-3-nitro)benzoate 

Downstream Products

• 888731-79-1 [6-(tert-butyldimethylsilyloxymethyl)-2,3-dihydrobenzo[1,4]oxazin-4-yl]-(3,5-dichloro-4-hydroxyphenyl)-methanone 

Relevant articles and documents

5-Quinoline derivatives having an anti-bacterial activity

The present invention describes novel anti-bacterial compounds of the formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase and topoisomerases, for example of topoisomerase II and IV.

Production Method of Nitrogen-Containing Fused Ring Compounds

[Problems] The present invention provides a superior production method and a superior purification method of compounds effective for the treatment or prophylaxis of pathology showing involvement of uric acid, such as hyperuricemia, gouty tophus, acute gouty arthritis, chronic gouty arthritis, gouty kidney, urolithiasis, renal function disorder, coronary artery disease, ischemic heart disease and the like. [Means] A compound represented by the following formula [2] or a pharmaceutically acceptable salt thereof can be produced by reacting a compound represented by the following formula [3] or a salt thereof with a compound represented by the following formula [4], a salt thereof or a reactive derivative thereof. Moreover, crystallization of a compound represented by the formula [2] can be performed with industrially superior workability, and high quality crystals of a compound represented by the formula [2] can be obtained. wherein each symbol is as defined in the description.

Nitrogen-containing fused ring compounds and use thereof

A URAT1 activity inhibitor containing a nitrogen-containing fused ring compound represented by the following formula [1]: wherein each symbol is as defined in the description. The present invention is useful for the prophylaxis or treatment of pathology showing involvement of uric acid, such as hyperuricemia, gouty tophus, acute gouty arthritis, chronic gouty arthritis, gouty kidney, urolithiasis, renal function disorder, coronary artery disease, ischemic heart disease and the like.

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Substituted 2H-1,4-benzoxazines were synthesized from substituted 2-amino phenols and 1,2-dibromoethane using K2CO3 in good to excellent yields. The cyclized products were further reacted with alkyl bromides to obtain the desired N-substituted 3,4-dihydro-2H-1,4-benzoxazines.

NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS

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