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916792-33-1

1-BOC-(R)-3-(2-METHOXYETHOXY)PYRROLIDINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 916792-33-1 Structure

  • Basic information

    1. Product Name: 1-BOC-(R)-3-(2-METHOXYETHOXY)PYRROLIDINE
    2. Synonyms: 1-BOC-(R)-3-(2-METHOXYETHOXY)PYRROLIDINE
    3. CAS NO:916792-33-1
    4. Molecular Formula: C12H23NO4
    5. Molecular Weight: 245.31532
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 916792-33-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-BOC-(R)-3-(2-METHOXYETHOXY)PYRROLIDINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-BOC-(R)-3-(2-METHOXYETHOXY)PYRROLIDINE(916792-33-1)
    11. EPA Substance Registry System: 1-BOC-(R)-3-(2-METHOXYETHOXY)PYRROLIDINE(916792-33-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 916792-33-1(Hazardous Substances Data)

916792-33-1 Usage

Chemical class

Pyrrolidine derivative

Protecting group

BOC (tert-butoxycarbonyl) attached to the nitrogen atom

Substituent

3-(2-methoxyethoxy), an ether functional group

Application

Organic synthesis

Use

Building block for pharmaceuticals and biologically active compounds

Stereochemistry

Specific stereochemistry contributes to its utility

Functional groups

Presence of ether and BOC groups allows for diverse chemical entity creation

Check Digit Verification of cas no

The CAS Registry Mumber 916792-33-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,6,7,9 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 916792-33:
(8*9)+(7*1)+(6*6)+(5*7)+(4*9)+(3*2)+(2*3)+(1*3)=201
201 % 10 = 1
So 916792-33-1 is a valid CAS Registry Number.

916792-33-1 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail

  • Alfa Aesar

  • (H50791)  1-Boc-(R)-3-(2-methoxyethoxy)pyrrolidine, 95%   

  • 916792-33-1

  • 250mg

  • 686.0CNY

  • Detail

  • Alfa Aesar

  • (H50791)  1-Boc-(R)-3-(2-methoxyethoxy)pyrrolidine, 95%   

  • 916792-33-1

  • 1g

  • 2743.0CNY

  • Detail

916792-33-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methyl-2-propanyl (3R)-3-(2-methoxyethoxy)-1-pyrrolidinecarboxy late

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:916792-33-1 SDS

916792-33-1Relevant articles and documents

NOVEL BETULINIC SUBSTITUTED AMIDE DERIVATIVES AS HIV INHIBITORS

-

, (2017/02/24)

The present invention relates to novel betulinic substituted amide compounds of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y, Z1, Z2, Z3 and are Formula (II) as defined herein. The invention novel betulinic substituted amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.

Discovery of highly potent and selective pan-Aurora kinase inhibitors with enhanced in vivo antitumor therapeutic index

Liu, Gang,Abraham, Sunny,Tran, Lan,Vickers, Troy D.,Xu, Shimin,Hadd, Michael J.,Quiambao, Sheena,Holladay, Mark W.,Hua, Helen,Ford Pulido, Julia M.,Gunawardane, Ruwanthi N.,Davis, Mindy I.,Eichelberger, Shawn R.,Apuy, Julius L.,Gitnick, Dana,Gardner, Michael F.,James, Joyce,Breider, Mike A.,Belli, Barbara,Armstrong, Robert C.,Treiber, Daniel K.

scheme or table, p. 3250 - 3260 (2012/06/01)

Serine/threonine protein kinases Aurora A, B, and C play essential roles in cell mitosis and cytokinesis. Currently a number of Aurora kinase inhibitors with different isoform selectivities are being evaluated in the clinic. Herein we report the discovery and characterization of 21c (AC014) and 21i (AC081), two structurally novel, potent, kinome-selective pan-Aurora inhibitors. In the human colon cancer cell line HCT-116, both compounds potently inhibit histone H3 phosphorylation and cell proliferation while inducing 8N polyploidy. Both compounds administered intravenously on intermittent schedules displayed potent and durable antitumor activity in a nude rat HCT-116 tumor xenograft model and exhibited good in vivo tolerability. Taken together, these data support further development of both 21c and 21i as potential therapeutic agents for the treatment of solid tumors and hematological malignancies.

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