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3,6-Difluoro-2-methoxyphenylboronic acid is a chemical compound characterized by the molecular formula C7H7BF2O3. It is a versatile reagent in the fields of organic synthesis and pharmaceutical research, known for its ability to bind with specific enzymes and proteins. This feature renders it a valuable asset in drug discovery and development. Moreover, its unique properties and reactivity contribute to its potential applications in agrochemicals and material science.

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  • 919355-30-9 Structure
  • Basic information

    1. Product Name: 3,6-DIFLUORO-2-METHOXYPHENYLBORONIC ACID
    2. Synonyms: 3,6-DIFLUORO-2-METHOXYPHENYLBORONIC ACID;(3,6-Difluoro-2-methoxyphenyl)
    3. CAS NO:919355-30-9
    4. Molecular Formula: C7H7BF2O3
    5. Molecular Weight: 187.936
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 919355-30-9.mol
  • Chemical Properties

    1. Melting Point: 99-101 °C(Solv: water (7732-18-5); hexane (110-54-3))
    2. Boiling Point: 313.3±52.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.35±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 7.32±0.58(Predicted)
    10. CAS DataBase Reference: 3,6-DIFLUORO-2-METHOXYPHENYLBORONIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3,6-DIFLUORO-2-METHOXYPHENYLBORONIC ACID(919355-30-9)
    12. EPA Substance Registry System: 3,6-DIFLUORO-2-METHOXYPHENYLBORONIC ACID(919355-30-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 919355-30-9(Hazardous Substances Data)

919355-30-9 Usage

Uses

Used in Pharmaceutical Research:
3,6-Difluoro-2-methoxyphenylboronic acid is used as a reagent for drug discovery and development due to its capacity to bind with certain enzymes and proteins. This interaction is crucial for the identification and creation of new therapeutic agents.
Used in Organic Synthesis:
In the realm of organic synthesis, 3,6-difluoro-2-methoxyphenylboronic acid is utilized as a key component in the synthesis of various organic compounds, contributing to the development of novel molecules with specific functions and properties.
Used in Suzuki-Miyaura Cross-Coupling Reactions:
3,6-Difluoro-2-methoxyphenylboronic acid is employed as a reactant in Suzuki-Miyaura cross-coupling reactions, a widely used method in organic chemistry for the formation of carbon-carbon bonds. This process is instrumental in the creation of new molecules and compounds with diverse applications.
Used in Agrochemicals:
3,6-Difluoro-2-methoxyphenylboronic acid is used in the development of agrochemicals, where its unique properties and reactivity can contribute to the creation of effective and targeted pesticides, herbicides, and other agricultural products.
Used in Material Science:
In the field of material science, 3,6-difluoro-2-methoxyphenylboronic acid is applied in the research and development of new materials with specific characteristics. Its reactivity and properties make it a promising candidate for enhancing material performance in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 919355-30-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,9,3,5 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 919355-30:
(8*9)+(7*1)+(6*9)+(5*3)+(4*5)+(3*5)+(2*3)+(1*0)=189
189 % 10 = 9
So 919355-30-9 is a valid CAS Registry Number.

919355-30-9Downstream Products

919355-30-9Relevant articles and documents

Small Molecule Inhibitors of KRAS G12C Mutant

-

Paragraph 0427-0428, (2021/04/30)

The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, M, L, Cy, Cz, R1, R2, R3, R4, R2a, Rs

Long-range effects in the metalation/boronation of functionalized 1,4-dihalobenzenes

Lulinski, Sergiusz,Serwatowski, Janusz,Zaczek, Anna

, p. 5167 - 5173 (2007/10/03)

The lithiation/boronation of 1,4-dihalobenzenes (Hal = F, Cl, Br) bearing various functional groups in the 2-position was investigated using lithium diisopropylamide (LDA) as the metalating agent and trialkyl borate B(OR) 3 (R = Et, iPr) as the

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