3,6-Difluoro-2-methoxyphenylboronic acid

Base Information

Chemical Name:3,6-Difluoro-2-methoxyphenylboronic acid
CAS No.:919355-30-9
Molecular Formula:C₇H₇BF₂O₃
Molecular Weight:187.939
Hs Code.:2931900090
European Community (EC) Number:829-054-0
DSSTox Substance ID:DTXSID20582373
Wikidata:Q82473785
Mol file:919355-30-9.mol

Synonyms:919355-30-9;3,6-Difluoro-2-methoxyphenylboronic acid;(3,6-Difluoro-2-methoxyphenyl)boronic acid;3,6-Difluoro-2-methoxybenzeneboronic acid;(3,6-Difluoro-2-methoxy-phenyl)boronic acid;SCHEMBL14120431;DTXSID20582373;MFCD11856009;AKOS006344039;AM804550;AS-39643;(3,6-Difluoro-2-methoxyphenyl)boronicacid;3,6-Difluoro-2-methoxybenzene boronic acid;CS-0133825;A860185

Suppliers and Price of 3,6-Difluoro-2-methoxyphenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,6-Difluoro-2-methoxyphenylboronicAcid
100mg
$ 60.00

Crysdot
(3,6-Difluoro-2-methoxyphenyl)boronicacid 95+%
1g
$ 402.00

AOBChem
3,6-Difluoro-2-methoxyphenylboronicacid 97%
5g
$ 312.00

AOBChem
3,6-Difluoro-2-methoxyphenylboronicacid 97%
500mg
$ 62.00

Alichem
3,6-Difluoro-2-methoxyphenylboronicacid
1g
$ 1685.00

Alichem
3,6-Difluoro-2-methoxyphenylboronicacid
250mg
$ 693.60

AK Scientific
3,6-Difluoro-2-methoxyphenylboronicacid
5g
$ 2494.00

Total 9 raw suppliers

Chemical Property of 3,6-Difluoro-2-methoxyphenylboronic acid

Chemical Property:

Melting Point:99-101 °C(Solv: water (7732-18-5); hexane (110-54-3))
Boiling Point:313.3±52.0 °C(Predicted)
PKA:7.32±0.58(Predicted)
Density:1.35±0.1 g/cm3(Predicted)
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:188.0456306
Heavy Atom Count:13
Complexity:170

Purity/Quality:

97% ^*data from raw suppliers

3,6-Difluoro-2-methoxyphenylboronicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B(C1=C(C=CC(=C1OC)F)F)(O)O

Technology Process of 3,6-Difluoro-2-methoxyphenylboronic acid

There total 2 articles about 3,6-Difluoro-2-methoxyphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 75626-17-4
2,5-difluoroanisole

: 919355-30-9
(3,6-difluoro-2-methoxyphenyl)boronic acid

Guidance literature:: 2,5-difluoroanisole; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -70 ℃; for 0.25h;

With triethyl borate; In tetrahydrofuran; hexane; at -70 ℃; for 0.25h;

With sulfuric acid; In tetrahydrofuran; hexane;
DOI:10.1002/ejoc.200600541

Reference yield:

: 121-43-7,63156-11-6
Trimethyl borate

: 75626-17-4
2,5-difluoroanisole

: 919355-30-9
(3,6-difluoro-2-methoxyphenyl)boronic acid

Guidance literature:: 2,5-difluoroanisole; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at 0 ℃; for 0.25h; Inert atmosphere;

Trimethyl borate; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h; Inert atmosphere;

With sulfuric acid; In tetrahydrofuran; hexane; water; at 0 ℃; for 2h;