A two-step, single pot procedure for the synthesis of substituted dihydropyrazolo-pyrimidines
In this study, we report a two-step, one pot tandem microwave-assisted reaction of 3-formylchromones with aminopyrazoles followed by a tin-free radical addition. A library of alkyl substituted dihydropyrazolopyrimidines was prepared using this new process.
Zimmerman, Jake R.,Myers, Brian J.,Bouhall, Samantha,McCarthy, Allison,Johntony, Olivia,Manpadi, Madhuri
supporting information
p. 936 - 940
(2015/03/03)
A two-step, single pot procedure for the synthesis of substituted dihydropyrazolo-pyrimidines
In this study, we report a two-step, one pot tandem microwave-assisted reaction of 3-formylchromones with aminopyrazoles followed by a tin-free radical addition. A library of alkyl substituted dihydropyrazolopyrimidines was prepared using this new process.
Zimmerman, Jake R.,Myers, Brian J.,Bouhall, Samantha,McCarthy, Allison,Johntony, Olivia,Manpadi, Madhuri
supporting information
p. 936 - 940
(2014/02/14)
Chlorotrimethylsilane mediated synthesis of 5-(2hydroxybenzoyl)pyrimidines from 3-formylchromones
The recyclization of 3-formylchromones with a variety of 1,3-NCNbinucleophiles promoted by chlorotrimethylsilane was investigated. A simple and flexible general procedure for the synthesis of series of 5-(2hydroxybenzoyl)pyrimidines and their heterofused analogues was proposed. A set of pyrimidines was obtained in high preparative yields.