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926273-98-5

N-(4-aminophenyl)-3,4-dichlorobenzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 926273-98-5 Structure

  • Basic information

    1. Product Name: N-(4-aminophenyl)-3,4-dichlorobenzamide
    2. Synonyms: N-(4-aminophenyl)-3,4-dichlorobenzamide
    3. CAS NO:926273-98-5
    4. Molecular Formula: C13H10Cl2N2O
    5. Molecular Weight: 281.14
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 926273-98-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(4-aminophenyl)-3,4-dichlorobenzamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(4-aminophenyl)-3,4-dichlorobenzamide(926273-98-5)
    11. EPA Substance Registry System: N-(4-aminophenyl)-3,4-dichlorobenzamide(926273-98-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 926273-98-5(Hazardous Substances Data)

926273-98-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 926273-98-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,6,2,7 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 926273-98:
(8*9)+(7*2)+(6*6)+(5*2)+(4*7)+(3*3)+(2*9)+(1*8)=195
195 % 10 = 5
So 926273-98-5 is a valid CAS Registry Number.

926273-98-5Downstream Products

926273-98-5Relevant articles and documents

Discovery of novel VEGFR-2 inhibitors embedding 6,7-dimethoxyquinazoline and diarylamide fragments

Wang, Ru,Liu, Hu,You, Yuan-Yuan,Wang, Xin-Yu,Lv, Bing-Bing,Cao, Li-Qin,Xue, Jia-Yu,Xu, Yun-Gen,Shi, Lei

, (2021/02/02)

VEGF/VEGFR-2 signaling plays a critical part in tumor angiogenesis. Inhibition of this pathway has been considered as a promising approach for cancer treatment. In this work, a series of 6,7-dimethoxy-4-anilinoquinazoline derivatives bearing diarylamide moiety were designed, synthesized and evaluated as potent inhibitors of VEGFR-2 kinase. Their in vitro antiproliferation activities against two human cancer cell lines Hep-G2 and MCF-7 have also been determined. Among them, compound 14b exhibited the most potent inhibitory activity against VEGFR-2 with IC50 value of 0.016 ± 0.002 μM and it showed the most potent antiproliferative effect against Hep-G2 and MCF-7 with IC50 values at low-micromolar range. Molecular docking studies revealed that these compounds represented by the most potent compound 14b could bind well to the ATP-binding site of VEGFR-2, which suggested that compound 14b could be a potential anticancer agent targeting VEGFR-2.

NAPHTHYRIDININONES AS AURORA KINASE INHIBITORS

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Page/Page column 54-55, (2010/04/03)

Naphthyridinone derivative compounds that inhibit Aurora kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative di

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