927180-06-1

Basic information

• Product Name: 1,2-Benzenedicarboxylic acid 1,2-bis-(2,5-dioxo-1-pyrrolidinyl) ester
• Synonyms: 1,2-Benzenedicarboxylic acid 1,2-bis-(2,5-dioxo-1-pyrrolidinyl) ester
• CAS NO: 927180-06-1
• Molecular Formula: C16H12N2O8
• Molecular Weight: 360.27508
• Mol File: 927180-06-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Benzenedicarboxylic acid 1,2-bis-(2,5-dioxo-1-pyrrolidinyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenedicarboxylic acid 1,2-bis-(2,5-dioxo-1-pyrrolidinyl) ester(927180-06-1)
• EPA Substance Registry System: 1,2-Benzenedicarboxylic acid 1,2-bis-(2,5-dioxo-1-pyrrolidinyl) ester(927180-06-1)

Safety Data

• Hazardous Substances Data: 927180-06-1(Hazardous Substances Data)

Usage

Chemical structure

1,2-Benzenedicarboxylic acid 1,2-bis-(2,5-dioxo-1-pyrrolidinyl) ester

Usage

Commonly used in the production of plastics and epoxy resins

Endocrine disruptor

Yes, it is a known endocrine disruptor

Health concerns

Linked to reproductive and developmental issues, obesity, and cancer

Exposure

Can leach from containers and food packaging into food and beverages, leading to widespread human exposure

Bans

Banned in the production of baby bottles and sippy cups in several countries

Regulatory status

Subject to ongoing regulatory scrutiny and restrictions

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 88-95-9 Phthaloyl dichloride 
• 88-99-3 benzene-1,2-dicarboxylic acid 

Relevant articles and documents

Insight into the complexation mode of Bis(nitrilotriacetic acid) (NTA) ligands with Ni2+ involved in the labeling of histidine-tagged proteins

According to literature reports and our own findings, the binding of new Ni2+-preloaded bis(nitrilotriacetic acid) (NTA) ligands with polyhistidine-tagged proteins has been found to be accompanied by a one- to twoorder-of-magnitude increase in

Multinuclear non-heme iron complexes for double-strand DNA cleavage

The cytotoxicity of the antitumor drug BLM is believed to be related to the ability of the corresponding iron complex (Fe-BLM) to engage in oxidative double-strand DNA cleavage. The iron complex of the ligand N4Py (Fe-N4Py; N4Py = N,N-bis(2-pyridyl)-N-bis

Double strand DNA cleavage with a binuclear iron complex

Covalently linking two single strand DNA cleaving agents resulted in a new biomimetic binuclear iron complex capable of effecting oxidative double strand DNA cleavage. The Royal Society of Chemistry.