928034-34-8Relevant articles and documents
DIAZASPIRODECANE OREXIN RECEPTOR ANTAGONISTS
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Page/Page column 38-39, (2008/06/13)
The present invention is directed to diazaspirodecane compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Spirocyclic compounds
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Page/Page column 55-56, (2008/06/13)
The present invention relates to a novel class of substituted spirocyclic compounds. These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of n