O8-benzyl O1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate

Base Information

• Chemical Name: O8-benzyl O1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate
• CAS No.: 928034-34-8
• Molecular Formula: C21H30N2O4
• Molecular Weight: 374.48
• Mol file: 928034-34-8.mol

Synonyms:

Chemical Property of O8-benzyl O1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate

Chemical Property:

• Vapor Pressure: 5.96E-10mmHg at 25°C

Purity/Quality:

≥98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of O8-benzyl O1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate

There total 1 articles about O8-benzyl O1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 1,8-diazaspiro[4.5]decane-1-carboxylate (885279-92-5) + benzyl chloroformate (501-53-1,94274-21-2) → 8-benzyl 1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate (928034-34-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 3.5h;

Reference yield:

8-benzyl 1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate (928034-34-8) → 8-[(benzyloxy)carbonyl]-8-aza-1-azoniaspiro[4.5]decane chloride (928034-35-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; at 0 - 20 ℃; for 24h;

Reference yield:

8-benzyl 1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate (928034-34-8) → C16H22N2O2 (928114-04-9)

Guidance literature:

8-benzyl 1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

With sodium hydrogencarbonate; In dichloromethane; water; ethyl acetate;

upstream raw materials:

tert-butyl 1,8-diazaspiro[4.5]decane-1-carboxylate

benzyl chloroformate

Downstream raw materials:

8-[(benzyloxy)carbonyl]-8-aza-1-azoniaspiro[4.5]decane chloride

C₁₆H₂₂N₂O₂

Refernces

• 1、 -. "Spirocyclic compounds". Page/Page column 55-56. . Retrieved 2008/06/13.