- Non-Nucleoside reverse transcriptase inhibitors
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Compounds of formula I, wherein R1, R2, R3, X and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.
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Page/Page column 15
(2009/01/23)
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- DISILYLATED COMPOUNDS AS PRECURSORS OF HETEROCYCLES: SYNTHESIS OF BENZIMIDAZOLES, TRIAZOLES, FURAN AND PYRROLE.
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The cyclization of disilylated compounds catalyzed by trifluoromethanesulfonoc acid is an easy way to obtain some heterocycles such as benzimidazole, triazole, furan and pyrrole.
- Rigo, Benoit,Valligny, Dominique,Taisne, Sophie
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p. 167 - 180
(2007/10/02)
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- ACETALS OF LACTAMS AND ACID AMIDES. 37. * REACTIONS OF AMIDE AND LACTAM ACETALS WITH DERIVATIVES OF UREA AND URETHANE AND SYNTHESIS OF CONDENSED PYRIMIDINES
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The reactions of diethylacetals of dimethylacetamide and N-methylbutyro-, -valero-, and -caprolactams with urea, thiourea, and urethane lead to the corresponding N-carbamide- and N-ethoxycarbonylamides, on the basis of which derivatives of pyrimidine and pyrrolo- and pyridopyrimidine and pyridoazepine, as well as triazole derivatives, were synthetized.
- Kaimanakova, S. I.,Kuleshova, E. F.,Solov'eva, N. P.,Granik, V. G.
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p. 1208 - 1211
(2007/10/02)
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