Synthesis and in vitro activity of 6-amino-2,9-diarylpurines for Mycobacterium tuberculosis
A mild method was developed to synthesize 6-amino-2-phenolic-9-alkyl and 9-arylpurines. The new compounds were screened for antibacterial activity against Mycobacterium tuberculosis strain H37Rv. The?9-tolyl derivatives with a dimethylamino or
Correia, Carla,Carvalho, M. Alice,Proen?a, M. Fernanda
experimental part
p. 6903 - 6911
(2009/12/09)
A domino type one-flask synthesis of 1-substituted-5-aminoimidazole-4- carboxamides and ring transformation to pyrazine under microwave through suitable aminoimidazoliumcarboxamide
Reductive heterocyclisation of oximinocyanoacetamide 1 in the presence of ethyl orthoformate and appropriate amine affords 1-substituted-5-aminoimidazole- 4-carboxamides 2. 4-Amino-5-carboxamido-3-diphenylmethyl-1-phenacylimidazolium bromide 4c, generated
Chattopadhyay, Gautam,Saha, Tapas K.
p. 827 - 830
(2007/10/03)
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