- BIOLOGICALLY ACTIVE COMPOUNDS SPECIFICALLY DELIVERED INTO MITOCHONDRIA
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This invention relates to biology and medicine and, in particular, can be used in medicine to make a pharmaceutical composition for targeted delivery of biologically active substances into mitochondria, driven by proton electro-chemical potential in the mitochondria. This invention also relates to the method to affect an organism by the targeted delivery of biologically active compounds to mitochondria. The invention can be useful in treatment of diseases or disorders associated with not normal functioning of mitochondria, in particular diseases associated with increased production of free radicals and reactive oxygen species.
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Paragraph 0109-0113
(2016/08/17)
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- PHARMACEUTICAL SUBSTANCES ON THE BASIS OF MITOCHONDRIALLY ADDRESSED ANTIOXIDANTS
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This invention relates to the fields of pharmaceutics and medicine, and, in particular, relates to the production and use of pharmaceutical substances on the basis of mitochondria-addressed compounds. The invention discloses methods for synthesis, purification and storage of mitochondria-addressed antioxidants, making it possible to produce said substances in a form and quality meeting the demands made on active ingredients of medicinal preparations - the pharmaceutical substances. The invention also discloses methods for design and selection of new mitochondria-addressed antioxidants having specified properties.
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Page/Page column 20
(2012/10/07)
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- PHARMACEUTICAL SUBSTANCES ON THE BASIS OF MITOCHONDRIA-ADDRESSED ANTIOXIDANTS
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This invention relates to the fields of pharmaceutics and medicine, and, in particular, relates to the production and use of pharmaceutical substances on the basis of mitochondria-addressed compounds. The invention discloses methods for synthesis, purification and storage of mitochondria-addressed antioxidants, making it possible to produce said substances in a form and quality meeting the demands made on active ingredients of medicinal preparations—the pharmaceutical substances. The invention also discloses methods for design and selection of new mitochondria-addressed antioxidants having specified properties.
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Page/Page column 17
(2012/10/18)
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- METHOD OF ACTING UPON ORGANISM BY TARGETED DELIVERY OF BIOLOGICALY ACTIVE SUBSTANCES INTO M ITOCHONDRIA, PHARMACEUTICAL COMPOSITION FOR CARRYING OUT SAID METHOD, AND COMPOUND USED FOR THE PURPOSE
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This invention relates to biology and medicine and, in particular, can be used in medicine to make a pharmaceutical composition for targeted delivery of biologically active substances into mitochondria, driven by proton electro-chemical potential in the mitochondria. This invention also relates to the method to affect an organism by the targeted delivery of biologically active compounds to mitochondria. The invention can be useful in treatment of diseases or disorders associated with not normal functioning of mitochondria, in particular diseases associated with increased production of free radicals and reactive oxygen species.
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Page/Page column 18-19
(2008/06/13)
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