Ethers of oximes with a carbostyril ring. IV. Syntheses and β-blocking activities
Syntheses of 12-O-(1-alkylamino-2-propanol)(8-hydroxy or alkoxycarbostyril)-5 methylketone oxime are reported. The beta-adrenergic blocking activity of the 12 compounds was determined in vitro on the trachea and atria of the guinea pig. Structure-activity relationships are discussed.
Amlaiky,Leclerc,Decker,Schwartz
p. 341 - 346
(2007/10/02)
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