Discovery of heterobicyclic templates for novel metabotropic glutamate receptor subtype 5 antagonists
Investigation of a series of heterobicyclic compounds with essential pharmacophoric features of the metabotropic glutamate receptor 5 (mGluR5) antagonists MPEP and MTEP provided novel structural templates with sub-micromolar affinities at the mGluR5.
Kulkarni, Santosh S.,Newman, Amy Hauck
p. 2987 - 2991
(2008/02/07)
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