Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels
In the present investigation, the rationale for the design, synthesis, and biological evaluation of potent inhibitors of neuronal Na+ channels is described. N,N'-Diaryl- and N-aryl-Naralkylguanidine templates were locked in conformations mimick
Maillard, Michel C.,Perlman, Michael E.,Amitay, Oved,Baxter, Deborah,Berlove, David,Connaughton, Sonia,Fischer, James B.,Guo, Jun Qing,Hu, Lain-Yen,McBurney, Robert N.,Nagy, Peter I.,Subbarao, Katragadda,Yost, Elizabeth A.,Zhang, Lu,Durant, Graham J.
p. 3048 - 3061
(2007/10/03)
More Articles about upstream products of 93982-96-8
