BICYCLIC DERIVATIVES AS SPHINGOSINE-1 -PHOSPHATE RECEPTORS MODULATORS
The present invention relates to novel bicyclic derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
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Page/Page column 27; 28;
(2015/11/16)
1,2,4-OXADIAZOL DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS SPHINGOSINE 1-PHOSPHATE 1 RECEPTOR AGONISTS
1,2,4-Oxadiazol derivatives represented by formula (I) useful as sphingosine 1-phosphate 1 (S1P1) receptor agonists, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders mediated via S1P1 receptor are disclosed.
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Page/Page column 47-48
(2010/12/31)
Molecular Design by Cycloaddition Reaction. Part 43. Cycloaddition Reactions of Silyl Enol Ethers of 2-Acetylfuran and -thiophene and Related Benzo Analogues
The title compounds (5, 6, 11, 12 and 13) underwent cycloaddition reactions with typical dienophiles followed by oxidative rearomatization.The reactions of (5) and (6) with heterodienophiles gave rather open-chain adducts via a zwitterionic interm
Sasaki, Tadashi,Ishibashi, Yukio,Ohno, Masatomi
p. 1972 - 1997
(2007/10/02)
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