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4-(4-Benzyl-piperazin-1-yl)-benzoic acid is a chemical compound characterized by the molecular formula C21H22N2O2. It features a benzoic acid molecule with a piperazine ring attached to a benzyl group at the 4th carbon position. 4-(4-BENZYL-PIPERAZIN-1-YL)-BENZOIC ACID is frequently utilized in pharmaceutical research and drug development, with a particular focus on the study of central nervous system disorders. Its unique structure and properties render it a valuable asset for researchers in the quest to develop novel therapies for a variety of medical conditions.

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  • 94038-26-3 Structure
  • Basic information

    1. Product Name: 4-(4-BENZYL-PIPERAZIN-1-YL)-BENZOIC ACID
    2. Synonyms: AKOS BB-5317;4-(4-BENZYL-PIPERAZIN-1-YL)-BENZOIC ACID;RARECHEM AL BE 1230;4-(4-Benzyl-1-piperazinyl)benzoic acid
    3. CAS NO:94038-26-3
    4. Molecular Formula: C18H20N2O2
    5. Molecular Weight: 296.36
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 94038-26-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 482.4°C at 760 mmHg
    3. Flash Point: 245.5°C
    4. Appearance: /
    5. Density: 1.216g/cm3
    6. Vapor Pressure: 4.08E-10mmHg at 25°C
    7. Refractive Index: 1.625
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 4-(4-BENZYL-PIPERAZIN-1-YL)-BENZOIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-(4-BENZYL-PIPERAZIN-1-YL)-BENZOIC ACID(94038-26-3)
    12. EPA Substance Registry System: 4-(4-BENZYL-PIPERAZIN-1-YL)-BENZOIC ACID(94038-26-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 94038-26-3(Hazardous Substances Data)

94038-26-3 Usage

Uses

Used in Pharmaceutical Research and Drug Development:
4-(4-Benzyl-piperazin-1-yl)-benzoic acid is used as a research tool for the development of new pharmaceuticals, specifically targeting central nervous system disorders. Its unique molecular structure allows it to interact with various biological targets, making it a promising candidate for the treatment of mood disorders and other neurological conditions.
Used in the Study of Central Nervous System Disorders:
In the field of neuroscience, 4-(4-Benzyl-piperazin-1-yl)-benzoic acid is employed as a compound of interest for understanding and potentially treating a range of neurological conditions. Its interaction with the central nervous system provides insights into the mechanisms underlying these disorders and aids in the development of targeted therapies.
Used in the Treatment of Mood Disorders:
4-(4-Benzyl-piperazin-1-yl)-benzoic acid is used as a potential therapeutic agent for mood disorders. Its ability to modulate neurotransmitter systems and influence the central nervous system makes it a candidate for the development of treatments aimed at alleviating the symptoms of such conditions.
Used in the Development of Neurological Condition Treatments:
In the realm of neurology, 4-(4-Benzyl-piperazin-1-yl)-benzoic acid is utilized in the research and development of treatments for various neurological conditions. Its potential to target specific pathways and receptors within the nervous system positions it as a valuable component in the creation of new therapeutic strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 94038-26-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,0,3 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 94038-26:
(7*9)+(6*4)+(5*0)+(4*3)+(3*8)+(2*2)+(1*6)=133
133 % 10 = 3
So 94038-26-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H20N2O2/c21-18(22)16-6-8-17(9-7-16)20-12-10-19(11-13-20)14-15-4-2-1-3-5-15/h1-9H,10-14H2,(H,21,22)

94038-26-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(4-benzylpiperazin-1-yl)benzoic acid

1.2 Other means of identification

Product number -
Other names 4-(4-BENZYL-PIPERAZIN-1-YL)-BENZOIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:94038-26-3 SDS

94038-26-3Relevant articles and documents

Base-Mediated Oxidative Degradation of Secondary Amides Derived from p-Amino Phenol to Primary Amides in Drug Molecules

Nanda, Kausik K.,Ginnetti, Anthony,Wuelfing, W. Peter

, p. 3394 - 3403 (2020/08/19)

One of the most common functional groups encountered in drug molecules is the amide, and the most common degradation pathway for amides is base-mediated hydrolysis to its constituent amine and carboxylic acid. Herein, we report for the first time, a base-

Benzamide nitriles

-

Page 34, (2010/02/09)

Compounds of the formula (I) wherein m, n, A, R1, R2, R3, R4, R5 and R6 are as described herein, together with methods for making the compounds and using the compounds for treatment of diseases or conditions mediated by Cathepsin K.

Substituted chroman derivatives

-

, (2008/06/13)

The present invention relates to new new piperidyl or piperazinyl-substituted dihydro-2H-1-benzopyran derivatives compound having the formula (I) wherein X is N or CH; Y is NR2CH2, CH2NR2, NR2CO, CONR

Substituted 1,2,3,4-tetrahydronaphthalene derivatives

-

, (2008/06/13)

PCT No. PCT/SE97/00469 Sec. 371 Date Apr. 25, 1997 Sec. 102(e) Date Apr. 25, 1997 PCT Filed Mar. 20, 1997 PCT Pub. No. WO97/34883 PCT Pub. Date Sep. 25, 1997New piperidinyl- or piperazinyl-substituted-1,2,3,4-tetrahydronaphthalene derivatives having the formula wherein X is N or CH; Y is NR2CH2, CH2-NR2, NR2-CO, CO-NR2 or NR2SO2; R1is H, C1-C6 alkyl or C3-C6 cycloalkyl; R3 is C1-C6 alkyl, C3-C6 cycloalkyl or (CH2)n-aryl, where aryl is phenyl or a heteroaromatic ring containing one or two heteroatoms selected from N, O and S and which may be mono- or di-substituted; n is 0-4; as (R)-enantiomer, (S)-enantiomer or a racemate in the form of the free base or a pharmaceutically acceptable salt or hydrate thereof; a pharmaceutical formulation containing the compounds, use of the compounds in the treatment of 5-hydroxytryptamine mediated disorders, processes for the preparation of the compounds and intermediates for the preparation of the compounds.

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