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943138-53-2

C10H10ClNO2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 943138-53-2 Structure

  • Basic information

    1. Product Name: C10H10ClNO2
    2. Synonyms: C10H10ClNO2
    3. CAS NO:943138-53-2
    4. Molecular Formula:
    5. Molecular Weight: 211.648
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 943138-53-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C10H10ClNO2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C10H10ClNO2(943138-53-2)
    11. EPA Substance Registry System: C10H10ClNO2(943138-53-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 943138-53-2(Hazardous Substances Data)

943138-53-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 943138-53-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,3,1,3 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 943138-53:
(8*9)+(7*4)+(6*3)+(5*1)+(4*3)+(3*8)+(2*5)+(1*3)=172
172 % 10 = 2
So 943138-53-2 is a valid CAS Registry Number.

943138-53-2Downstream Products

943138-53-2Relevant articles and documents

Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids

Wang, Gary T.,Mantei, Robert A.,Kawai, Megumi,Tedrow, Jason S.,Barnes, David M.,Wang, Jieyi,Zhang, Qian,Lou, Pingping,Garcia, Lora A.,Bouska, Jennifer,Yates, Melinda,Park, Chang,Judge, Russell A.,Lesniewski, Richard,Sheppard, George S.,Bell, Randy L.

, p. 2817 - 2822 (2008/02/03)

A series of aryl sulfonamides of 5,6-disubstituted anthranilic acids were identified as potent inhibitors of methionine aminopeptidase-2 (MetAP2). Small alkyl groups and 3-furyl were tolerated at the 5-position of anthranilic acid, while -OCH3, CH3, and Cl were found optimal for the 6-position. Placement of 2-aminoethoxy group at the 6-position enabled interaction with the second Mn2+ but did not result in enhancement in potency. Introduction of a tertiary amino moiety at the ortho-position of the sulfonyl phenyl ring gave reduced protein binding and improved cellular activity, but led to lower oral bioavailability.

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