Structure-based design of 2-arylamino-4-cyclohexylmethoxy-5-nitroso-6- aminopyrimidine inhibitors of cyclin-dependent kinase 2
An efficient synthesis of 2-substituted O4-cyclohexylmethyl-5- nitroso-6-aminopyrimidines from 6-amino-2-mercaptopyrimidin-4-ol has been developed and used to prepare a range of derivatives for evaluation as inhibitors of cyclin-dependent kinas
Marchetti, Francesco,Sayle, Kerry L.,Bentley, Johanne,Clegg, William,Curtin, Nicola J.,Endicott, Jane A.,Golding, Bernard T.,Griffin, Roger J.,Haggerty, Karen,Harrington, Ross W.,Mesguiche, Veronique,Newell, David R.,Noble, Martin E. M.,Parsons, Rachel J.,Pratt, David J.,Wang, Lan Z.,Hardcastle, Ian R.
p. 1577 - 1585
(2008/02/04)
More Articles about upstream products of 945618-75-7