945744-04-7

Basic information

• Product Name: 2-Di(tert-butyloxycarbonyl)-L-hoMoserine tert-Butyl Ester
• Synonyms: 2-Di(tert-butyloxycarbonyl)-L-hoMoserine tert-Butyl Ester
• CAS NO: 945744-04-7
• Molecular Formula: C18H33NO7
• Molecular Weight: 375.45712
• Product Categories: Aliphatics;Amino Acids & Derivatives;Aliphatics, Amino Acids & Derivatives
• Mol File: 945744-04-7.mol

Chemical Properties

• Boiling Point: 443.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.099±0.06 g/cm3(Predicted)
• Solubility: Dichloromethane, Methanol
• PKA: 14.58±0.10(Predicted)
• CAS DataBase Reference: 2-Di(tert-butyloxycarbonyl)-L-hoMoserine tert-Butyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Di(tert-butyloxycarbonyl)-L-hoMoserine tert-Butyl Ester(945744-04-7)
• EPA Substance Registry System: 2-Di(tert-butyloxycarbonyl)-L-hoMoserine tert-Butyl Ester(945744-04-7)

Safety Data

• Hazardous Substances Data: 945744-04-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Di(tert-butyloxycarbonyl)-L-hoMoserine tert-Butyl Ester is used as an intermediate in the preparation of aspartyl aldehyde derivatives, which are important compounds in the development of pharmaceuticals targeting various diseases. Its unique structure allows for the synthesis of complex molecules with potential therapeutic applications.
Used in Biochemistry Research:
In the field of biochemistry, 2-Di(tert-butyloxycarbonyl)-L-hoMoserine tert-Butyl Ester is used as an intermediate for the synthesis of labelled L-Glutamine (G597000). This labelled compound is essential for research purposes, particularly in studying the metabolism and function of L-Glutamine in biological systems. The use of this intermediate enables the production of labelled L-Glutamine, which can be utilized in various experimental setups to gain insights into its role in cellular processes.

Upstream product

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• 94347-11-2 4-benzyl 1-t-butyl L-aspartate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 395095-60-0 1-tert-butyl 4-methyl (2S)-2-{(tert-butoxy)-N-[(tert-butyl)oxycarbonyl]carbonylamino}butanedioate 
• 269733-22-4 N,N-Bis(tert-butoxycarbonyl)-L-aspartic acid α-tert-butyl ester 

Relevant articles and documents

INHIBITORS OF DNMT1 AS ANTICANCER THERAPEUTIC AGENTS

Inhibitors of DNA methyltransferase 1 (an enzyme responsible for the maintenance of DNA CpG methylation marks in human cells) and their use as therapeutic agents against various cancers. The invention relates to compounds, pharmaceutical compositions, met

An unexpected product from attempted reductive etherification of a silyl alcohol with an aldehyde

Reductive etherification, using BiBr3/Et3SiH, between two modified amino acids, one with a silyl alcohol side chain and one with an aldehyde side chain, gave, not the desired bis-amino acid, but a tetrahydrooxazine, in good yield.

Asymmetric synthesis of differentially protected meso-2,6-diaminopimelic acid

meso-2,6-Diaminopimelic acid, an important linking component of bacterial cell walls and a biosynthetic precursor of L-lysine has been prepared differentially protected in a stereospecific manner from both L-aspartic and L-glutamic acid. The key step to establish the second chiral center involves the asymmetric reduction of a pyruvate moiety with Alpine-Borane. S-2-Amino-6-oxopimelic acid, the hydrolyzed open chain form of tetrahydrodipicolinic acid, a biosynthetic precursor of meso-2,6-diaminopimelic acid, was also prepared via deprotection of the key pyruvate intermediate.