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N-Isopropyl 2-bromobenzenesulfonamide is a chemical compound characterized by a benzene ring with a sulfonamide group, a bromine atom, and an isopropyl group attached to it. It is recognized for its potential in various applications due to its unique structure and properties.

951883-94-6

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951883-94-6 Usage

Uses

Used in Organic Synthesis:
N-Isopropyl 2-bromobenzenesulfonamide is utilized as a reagent in organic synthesis for its ability to facilitate the formation of new chemical bonds and structures, contributing to the creation of a wide range of organic compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, N-Isopropyl 2-bromobenzenesulfonamide is employed as a reagent to assist in the development and synthesis of new drugs, leveraging its chemical properties to enhance drug discovery processes.
Used in Antimicrobial Applications:
N-Isopropyl 2-bromobenzenesulfonamide is used as an antimicrobial agent for its ability to inhibit the growth of microorganisms, making it a valuable component in biocidal products designed to combat microbial contamination.
Used in Fungicidal Applications:
Similarly, its fungicidal properties position N-Isopropyl 2-bromobenzenesulfonamide as an ingredient in products aimed at controlling fungal growth, offering protection against fungal infestations in various settings.
Used in the Development of New Drugs:
N-Isopropyl 2-bromobenzenesulfonamide holds potential in the development of new pharmaceuticals, where its unique structure may contribute to the creation of novel therapeutic agents with specific medicinal properties.
Used in Dyes and Pigments Manufacturing:
N-Isopropyl 2-bromobenzenesulfonamide is also applied in the manufacturing of dyes and pigments, capitalizing on its chemical composition to produce a range of colorants for various industries.
It is crucial to handle N-Isopropyl 2-bromobenzenesulfonamide with care due to its potential hazards if not properly managed, emphasizing the need for safety measures in its application and use.

Check Digit Verification of cas no

The CAS Registry Mumber 951883-94-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,1,8,8 and 3 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 951883-94:
(8*9)+(7*5)+(6*1)+(5*8)+(4*8)+(3*3)+(2*9)+(1*4)=216
216 % 10 = 6
So 951883-94-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H12BrNO2S/c1-7(2)11-14(12,13)9-6-4-3-5-8(9)10/h3-7,11H,1-2H3

951883-94-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-N-propan-2-ylbenzenesulfonamide

1.2 Other means of identification

Product number -
Other names 2-Bromo-N-isopropylbenzenesulfonamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:951883-94-6 SDS

951883-94-6Relevant articles and documents

Structurally Diverse Synthesis of Five-, Six-, and Seven-Membered Benzosultams through Electrochemical Cyclization

Liu, Aiyun,Guo, Tiantian,Zhang, Shuangshuang,Yang, Han,Zhang, Qi,Chai, Yonghai,Zhang, Shengyong

supporting information, p. 6326 - 6331 (2021/08/23)

We have developed a metal- and oxidant-free approach to structurally diverse synthesis of benzosultams from aryl sulfonamides through an electrochemical cyclization. Upon variation of the ortho substituent on aryl sulfonamides, five-, six-, and seven-memb

Palladium-catalyzed C-C coupling of aryl halides with isocyanides: An alternative method for the stereoselective synthesis of (3E)-(Imino)isoindolin- 1-ones and (3E)-(imino)thiaisoindoline 1,1-dioxides

Liu, Bifu,Li, Yibiao,Jiang, Huanfeng,Yin, Meizhou,Huang, Huawen

, p. 2288 - 2300 (2012/11/07)

A palladium-catalyzed, one-pot cyclization reaction to construct (3E)-(imino)isoindolin-1-ones and (3E)-(imino)thiaisoindoline 1,1-dioxides by introducing ortho-reactive functional groups on aryl halides is reported. Under optimal conditions, the cyclization reaction afforded the corresponding products in good to excellent yields (up to 93%) with high stereoselectivity. Notably, this transformation successfully extends its application for the synthesis of phenanthridines and dibenzooxazepines. This new synthetic protocol not only extends the application platform for palladium-catalyzed C-C coupling of aryl halides with isocyanides, but also opens atom-economic and step-economic synthetic routes for nitrogen-containing heterocyclic compounds with wide functional group compatibility. Copyright

Design and discovery of a selective small molecule κ opioid antagonist (2-methyl- n -((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl) methyl)propan-1-amine, PF-4455242)

Verhoest, Patrick R.,Sawant Basak, Aarti,Parikh, Vinod,Hayward, Matthew,Kauffman, Gregory W.,Paradis, Vanessa,McHardy, Stanton F.,McLean, Stafford,Grimwood, Sarah,Schmidt, Anne W.,Vanase-Frawley, Michelle,Freeman, Jodi,Van Deusen, Jeffrey,Cox, Loretta,Wong, Diane,Liras, Spiros

experimental part, p. 5868 - 5877 (2011/10/08)

By use of parallel chemistry coupled with physicochemical property design, a series of selective κ opioid antagonists have been discovered. The parallel chemistry strategy utilized key monomer building blocks to rapidly expand the desired SAR space. The potency and selectivity of the in vitro κ antagonism were confirmed in the tail-flick analgesia model. This model was used to build an exposure-response relationship between the ? Ki and the free brain drug levels. This strategy identified 2-methyl-N-((2′- (pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine, PF-4455242, which entered phase 1 clinical testing and has demonstrated target engagement in healthy volunteers.

PHENETHANOLAMINE DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES

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Page 44-45, (2010/02/06)

The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.

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