7154-66-7

Basic information

• Product Name: 2-Bromobenzoyl chloride
• Synonyms: 2-BROMOBENZOYL CHLORIDE;2-BROMOBENZENE-1-CARBONYL CHLORIDE;O-BROMOBENZOYL CHLORIDE;o-bromo-benzoylchlorid;Benzoyl chloride, 2-bromo-;2-Bromobenzoic acid chloride;2-Bromobenzoyl chloride,98%;o-bromobenzoyl chloride(2-
• CAS NO: 7154-66-7
• Molecular Formula: C₇H₄BrClO
• Molecular Weight: 219.46
• EINECS: 230-507-4
• Product Categories: Aromatic Halides (substituted);Acid Halides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 7154-66-7.mol
• Article Data: 107

Chemical Properties

• Melting Point: 8-10 °C(lit.)
• Boiling Point: 245 °C(lit.)
• Flash Point: >230 °F
• Appearance: Clear colorless to light yellow/Liquid
• Density: 1.679 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0283mmHg at 25°C
• Refractive Index: n20/D 1.597(lit.)
• Storage Temp.: 0-6°C
• Sensitive: Moisture Sensitive
• BRN: 508506
• CAS DataBase Reference: 2-Bromobenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromobenzoyl chloride(7154-66-7)
• EPA Substance Registry System: 2-Bromobenzoyl chloride(7154-66-7)

Safety Data

• Hazard Codes: C
• Statements: 34-37
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• RTECS: DM6635000
• F: 8-10-19-21
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 7154-66-7(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLOURLESS TO LIGHT YELLOW LIQUID

InChI:InChI=1/C7H4BrClO/c8-6-4-2-1-3-5(6)7(9)10/h1-4H

Upstream product

• 118-92-3 anthranilic acid 
• 55666-42-7 tert-butyl 2-bromobenzoate 
• 7719-12-2 phosphorus trichloride 
• 88-65-3 2-bromobenzoic-acid 
• 586-76-5 4-Bromobenzoic acid 
• 79-37-8 oxalyl dichloride 
• 108-86-1 bromobenzene 

Downstream Products

• 95096-11-0 N-Benzyl-2-bromo-N-hydroxy-benzamide 
• 61593-14-4 1-(2-bromophenyl)-2,2-dimethyl-propan-1-one 
• 197149-78-3 Dimethyl 2-bromobenzoylphosphonate 
• 136272-09-8 4-chlorobutyl o-bromobenzoate 
• 49619-44-5 2-bromobenzoic anhydride 
• 72083-01-3 4-{[1-(5-Bromo-2-hydroxy-phenyl)-1-(2-bromo-phenyl)-meth-(E)-ylidene]-amino}-butyric acid 
• 65246-98-2 5-Brom-2'-brom-2-aminobenzophenon 
• 64358-20-9 (2-bromophenyl)(2,4-dimethylphenyl)methanone 
• 66896-72-8 N-(2-Bromo-benzoyl)-N-methyl-benzenesulfonamide 
• 64358-19-6 2-Bromo-4'-n-octyl-benzophenone 
• 64358-18-5 2-Bromo-4'-n-amyl-benzophenone 
• 64358-17-4 2-bromo-4'-(n-butyl)benzophenone 
• 64358-16-3 (2-Bromo-phenyl)-(4-propyl-phenyl)-methanone 
• 72083-06-8 4-{[1-(2-Bromo-phenyl)-1-(5-chloro-2-hydroxy-phenyl)-meth-(E)-ylidene]-amino}-butyramide 

Relevant articles and documents

Cavity-extended inherently chiral resorcin[4]arenes: Synthesis and chiroptical properties of the cycloenantiomers

Inherently chiral resorcin[4]arenes 2 and 3 were prepared from enantiomerically pure C4-symmetric rccc-2,8,14,20-tetraisobutyl-4,10, 16,22-tetra-O-methylresorcin[4]arene (1). The four 2-bromobenzyl ether residues in precursor 2 were introduced

6-Arylphenanthridines from Aryl o-Biaryl Ketones with 1,1,1,3,3,3-Hexamethyldisilazane and Molecular Iodine

Warming treatment of aryl o-biaryl ketones with 1,1,1,3,3,3-hexamethyldisilazane in the presence of Sc(OTf)3 in toluene, followed by the reaction with molecular iodine and K2CO3 in a mixture of THF and methanol at 60 °C gave the corresponding 6-arylphenanthridines in good to moderate yields. The present reaction is a one-pot method for the preparation of 6-arylphenanthridines from aryl o-biaryl ketones through the cyclization of imino-nitrogen-centered radicals that were generated from N-iodo aryl o-biaryl ketimines formed from the reaction of aryl biaryl ketimines with molecular iodine.

Method for synthesizing chlorantraniliprole derivative intermediate

The invention provides a method for synthesizing a chlorantraniliprole derivative intermediate, belonging to the field of agricultural pesticides. The method comprises the following steps: subjectingthe intermediate 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid to chlorination so as to prepare 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-formyl chloride; subjecting the raw material 2-bromobenzoic acid to acylating chlorination and ammoniation so as to prepare substituted 2-bromo-benzamide; and subjecting 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-formyl chloride and substituted 2-bromo-benzamide to cyclization so as to obtain the chlorantraniliprole derivative intermediate. The method of the invention is simple and common; reagents used in the process of synthesis are low in toxicity, used solvents are recyclable, and few by-products are produced, so the method has little corrosion to equipment and low pollution to environment; since raw materials are cheap, production cost is reduced and good economical efficiency is obtained; therefore, the method has good application prospects.