951884-00-7

Basic information

• Product Name: (6-chloropyrazin-2-yl)isopropylamine
• Synonyms: (6-chloropyrazin-2-yl)isopropylamine;6-Chloro-N-isopropylpyrazin-2-amine, 6-Chloro-N-(prop-2-yl)pyrazin-2-amine, 2-Chloro-6-(isopropylamino)-1,4-diazine
• CAS NO: 951884-00-7
• Molecular Formula: C₇H₁₀ClN₃
• Molecular Weight: 171.63
• Product Categories: Amines;blocks;Pyridines
• Mol File: 951884-00-7.mol

Chemical Properties

• Boiling Point: 270.1 °C at 760 mmHg
• Flash Point: 117.2 °C
• Appearance: /
• Density: 1.22 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (6-chloropyrazin-2-yl)isopropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (6-chloropyrazin-2-yl)isopropylamine(951884-00-7)
• EPA Substance Registry System: (6-chloropyrazin-2-yl)isopropylamine(951884-00-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 951884-00-7(Hazardous Substances Data)

Usage

Uses

2-Chloro-6-isopropylaminopyrazine

Upstream product

• 4774-14-5 2,6-dichloropyrazine 
• 75-31-0 isopropylamine 

Downstream Products

• 1401349-91-4 3-(3-(6-(isopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-84-5 3-(3-(6-(isopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-thiadiazol-5-amine 
• 1401349-83-4 tert-butyl (3-(3-(6-(isopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-thiadiazol-5-yl)carbamate 
• 1401349-77-6 5-(3-(6-(isopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-thiadiazol-3-amine 
• 1401349-76-5 5-(3-(6-(isopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-N-(4-methoxybenzyl)-1,2,4-thiadiazol-3-amine 

Relevant articles and documents

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

AZOLE COMPOUNDS AS PIM INHIBITORS

The invention relates to bicyclic compounds of formulas I and Ia, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further em