953039-10-6

Basic information

• Product Name: 8-Quinazolinol, 2-chloro-
• Synonyms: 8-Quinazolinol, 2-chloro-;2-chloro-quinazolin-8-ol;2-Chloro-8-quinazolinol
• CAS NO: 953039-10-6
• Molecular Formula: C₈H₅ClN₂O
• Molecular Weight: 180.5911
• Mol File: 953039-10-6.mol

Chemical Properties

• Boiling Point: 325.3±24.0 °C(Predicted)
• Appearance: /
• Density: 1.500±0.06 g/cm3(Predicted)
• PKA: 8.30±0.40(Predicted)
• CAS DataBase Reference: 8-Quinazolinol, 2-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Quinazolinol, 2-chloro-(953039-10-6)
• EPA Substance Registry System: 8-Quinazolinol, 2-chloro-(953039-10-6)

Safety Data

• Hazardous Substances Data: 953039-10-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
8-Quinazolinol, 2-chlorois used as a key intermediate in the synthesis of various drugs and pharmaceutical compounds. Its unique chemical structure and properties make it a valuable starting material for the development of new medications with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2-chloro-8-quinazolinol is utilized as a building block for the synthesis of various agrochemicals, such as pesticides and herbicides. Its chemical properties allow for the creation of effective and targeted agrochemicals to protect crops and enhance agricultural productivity.
Used in Specialty Chemicals Industry:
8-Quinazolinol, 2-chlorois also used in the production of specialty chemicals, which are high-value chemicals with specific applications in various industries. Its unique structure and reactivity make it suitable for the synthesis of advanced materials, dyes, and other specialty chemicals.
Used in Medicinal Chemistry Research:
2-chloro-8-quinazolinol is being studied for its pharmacological properties, as it has potential medicinal uses. Researchers are exploring its interactions with biological targets and evaluating its efficacy in treating various diseases and conditions.
Overall, 8-Quinazolinol, 2-chlorois an important compound with diverse industrial and pharmaceutical applications, making it a valuable asset in the development of new products and technologies across various industries.

Upstream product

• 70127-96-7 2-amino-3-methoxy-benzaldehyde 
• 53055-05-3 3-methoxy 2-nitrobenzaldehyde 
• 858452-80-9 8-methoxyquinazolin-2-ol 
• 944060-66-6 2-chloro-8-methoxyquinazoline 

Downstream Products

• 953039-39-9 C₁₁H₁₁ClN₂O 
• 953039-49-1 tert-butyl 4-((2-chloroquinazolin-8-yl)oxy)piperidine-1-carboxylate 
• 953040-03-4 5-bromo-2-chloro-quinazolin-8-ol 
• 953039-17-3 7-bromo-2-chloro-quinazolin-8-ol 
• 953040-05-6 tert-butyl 4-(5-bromo-2-(2-chloro-4-morpholin-4-yl-phenylamino)quinazolin-8-yloxy)-piperidine-1-carboxylate 
• 953040-09-0 2,5-dichloro-8-methoxy-quinazoline 
• 953039-87-7 7-bromo-2,5-dichloro-quinazolin-8-ol 
• 953039-88-8 7-bromo-2,5-dichloro-8-methoxy-quinazoline 

Relevant articles and documents

Novel quinazoline derivative

The present invention provides a quinazoline derivative represented by formula (I) (in the formula, R1 and R2 represent a hydrogen atom, a halogen atom, or a lower alkyl group optionally having a substituent group, Z represents a cycloakyl group having a

QUINAZOLINES FOR PDK1 INHIBITION

The invention provides novel quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.