Welcome to LookChem.com Sign In|Join Free

CAS

  • or

956-90-1

Phencyclidine hydrochloride (PCP), also known as 1-(1-phenylcyclohexane)piperidine, is a psychoactive drug that exhibits a range of effects on the central nervous system, including inhibitory, excitatory, analgesic, and hallucinogenic properties. It is a crystalline solid and is classified as a dissociative drug. PCP was once utilized by anesthesiologists as an intravenous anesthetic, but its hallucinogenic and neurotoxic effects led to its discontinuation in this context.

956-90-1 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn't provide relevant sales information.
  • 956-90-1 Structure

  • Basic information

    1. Product Name: PHENCYCLIDINE HYDROCHLORIDE
    2. Synonyms: 1-(1-phenylcyclohexyl)-piperidinhydrochloride;cn-25,253-2;elysion;gp-121;mcv4158;nih9580;nsc-40902;pcphydrochloride
    3. CAS NO:956-90-1
    4. Molecular Formula: C17H25N*ClH
    5. Molecular Weight: 279.85
    6. EINECS: N/A
    7. Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 956-90-1.mol

  • Chemical Properties

    1. Melting Point: 233-235°C
    2. Boiling Point: 340°C at 760 mmHg
    3. Flash Point: 144.5°C
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 8.86E-05mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: Store at RT
    9. Solubility: H2O: 11.2 mg/mL
    10. CAS DataBase Reference: PHENCYCLIDINE HYDROCHLORIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: PHENCYCLIDINE HYDROCHLORIDE(956-90-1)
    12. EPA Substance Registry System: PHENCYCLIDINE HYDROCHLORIDE(956-90-1)

  • Safety Data

    1. Hazard Codes: T
    2. Statements: 25
    3. Safety Statements: 36/37-45
    4. RIDADR: UN 2811 6.1/PG 3
    5. WGK Germany: 3
    6. RTECS: TN2272600
    7. HazardClass: 6.1(a)
    8. PackingGroup: I
    9. Hazardous Substances Data: 956-90-1(Hazardous Substances Data)

956-90-1 Usage

Uses

Used in Pharmaceutical Industry:
Phencyclidine hydrochloride is used as a controlled substance for its depressant effects on the central nervous system. It was historically employed as an anesthetic due to its ability to induce a state of dissociative anesthesia, characterized by a lack of sensation and perception while maintaining muscle tone and reflexes.
Used in Research and Forensic Applications:
PCP is utilized in research settings to study the effects of dissociative drugs on the central nervous system and to develop potential treatments for neurological disorders. Additionally, it is used in forensic applications for the detection and analysis of the drug in cases of substance abuse or criminal activity.

Biological Activity

Non-competitive NMDA receptor antagonist and sigma receptor agonist. Psychostimulant; induces rotational behavior, head-weaving and cognitive dysfunction in rats.

Biochem/physiol Actions

σ opioid receptor agonist and psychostimulant; inhibits NMDA glutamate receptor activation by binding to an allosteric site within the ion channel.

Safety Profile

Poison by ingestion,subcutaneous, intravenous, and intraperitoneal routes.Human systemic effects by ingestion and intravenousroutes: distorted perceptions, euphoria, excitement,hallucinations, and paresthesia. An experimental teratogen.Other experime

Check Digit Verification of cas no

The CAS Registry Mumber 956-90-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,5 and 6 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 956-90:
(5*9)+(4*5)+(3*6)+(2*9)+(1*0)=101
101 % 10 = 1
So 956-90-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H25N.ClH/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18;/h1,4-5,10-11H,2-3,6-9,12-15H2;1H

956-90-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(1-phenylcyclohexyl)piperidine,hydrochloride

1.2 Other means of identification

Product number -
Other names Sernyl hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:956-90-1 SDS

956-90-1Relevant articles and documents

New morpholine analogues of phencyclidine: Chemical synthesis and pain perception in rats

Ahmadi, Abbas,Khalili, Mohsen,Hajikhani, Ramin,Naserbakht, Moslem

, p. 227 - 233 (2013/01/09)

Phencyclidine (PCP, I) and most its derivatives have demonstrated some pharmacological effects. Accordingly, in this study, the new methoxy (III) and hydroxy-methyl (IV) morpholine PCP derivatives were synthesized. The acute and chronic pain activities of these drugs (III, IV) were investigated by tail immersion and formalin tests on rats and the results were compared with those in PCP, PCM (PCP-morpholine, II), and methyl-PCM (V). Findings indicated that III (6 mg/kg, i.p.) generates more analgesic effects in tail immersion test in comparison with I and II in 20, 40, 45 and 55 min post-injection. These effects were observed in 10, 20, 40, 45 and 50 min after the application of IV (at the same dosage). This analgesic effect was markedly seen in 20, 40, 45 and 50 min after compound IVs application in comparison with the drugs (I-V). In formalin test analysis, the acute chemical pain (Phase I) could not be affected by any drugs (I-V) while chronic formalin pain would be diminished by these new synthesized drugs (III and IV), especially in late Phase II, compared to I and II at the dosage of 6 mg/kg. It is, therefore, concluded that these new synthesized PCP derivates including methoxy-PCM (III) and hydroxy-methyl-PCM (IV) could substantially and respectively diminish acute thermal and chronic chemical pains.