cas 96232-71-2, METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE | Articles data ｜lookchem

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96232-71-2

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N-1H-Tetrazol-5-yl-(5-Ring)-carboxamide-derivatives, a process for their manufacture, and the use thereof
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(2008/06/13)

Organic compounds and their use as pharmaceuticals
Compounds of the following formula have pharmacutical properties: STR1 in which R1 and R2 independently are hydrogen, halo, nitro, amino, C2-5 acylamino, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylsulphonyl, N-substituted heterocyclyl, optionally substituted phenyl, optionally substituted phenylthio, optionally substituted phenylsulphonyl or optionally substituted phenylsulphonamido, or R1 and R2 together form a C3-5 alkylene bridge, R3 is C1-4 alkyl or C2-4 alkenyl, and X is (i) --(CH2)n N(R4)2 where each R4 independently is C1-4 alkyl, C2-4 alkenyl or optionally substituted C6 H5 CH2 --, and n is 1, 2 or 3, or (ii) a 5- to 8-membered alicyclic group containing one or two nitrogen atoms and directly attached to the amido nitrogen or attached by a C1-3 alkylene chain; and salts thereof.
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(2008/06/13)

N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof
The present invention is for compounds having the formula of N-1H-tetrazol-5-yl-2-thiophenecarboxamides, N-1H-tetrazol-5-yl-2-pyrrolecarboxamides, N-1H-tetrazol-5-yl-2-furancarboxamides or analogs of each of the carboxamides. The compounds are useful for the treatment of allergic or inflammatory conditions or diseases. Thus, pharmaceutical compositions and methods of use are also the invention. Processes of preparation for the compounds are also the invention.
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(2008/06/13)

Reactions with 3-hydroxy-2-methoxycarbonylthiophene; I. Synthesis of 3-thienyloxyacetic acid and its (Nuclear) chloro and bromo derivatives
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Corral,Lissavetzky
p. 847 - 850
(2007/10/02)

More Articles about upstream products of 96232-71-2

5118-06-9
methyl 3-hydroxy-2-thiophenecarboxylate

More Articles about downstream products of 96232-71-2

Chemical Properties

Melting Point: 125-128°C
Boiling Point: 321.6°Cat760mmHg
Flash Point:148.3°C
Density: 2.394g/cm³
Vapor Pressure: 0.00113mmHg at 25°C
PKA: 6.97±0.20(Predicted)
PSA: 74.77000
LogP: 2.76530

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