96232-71-2

Basic information

• Product Name: METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE
• Synonyms: METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE;4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
• CAS NO: 96232-71-2
• Molecular Formula: C₆H₄Br₂O₃S
• Molecular Weight: 315.97
• Mol File: 96232-71-2.mol

Chemical Properties

• Melting Point: 125-128°C
• Boiling Point: 321.6°Cat760mmHg
• Flash Point: 148.3°C
• Appearance: /
• Density: 2.394g/cm³
• Vapor Pressure: 0.00113mmHg at 25°C
• Refractive Index: 1.647
• PKA: 6.97±0.20(Predicted)
• CAS DataBase Reference: METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE(96232-71-2)
• EPA Substance Registry System: METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE(96232-71-2)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 96232-71-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE is used as an intermediate in organic synthesis for its ability to contribute to the formation of various functional materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE is used as a building block for the development of pharmaceutical ingredients, leveraging its unique chemical structure to create novel therapeutic agents.
Used in Agrochemicals:
METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE is utilized in the agrochemical sector as an intermediate for the synthesis of agrochemicals, contributing to the development of effective crop protection products.
Used in Organic Electronics:
Due to its electronic properties, METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE is used in the field of organic electronics, where it may be incorporated into the design of electronic devices and materials.
Used in Material Development:
Its structure and properties make METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE useful in the development of new chemical compounds and materials, where it can enhance the properties of existing materials or contribute to the creation of innovative products.

InChI:InChI=1/C6H4Br2O3S/c1-11-6(10)4-3(9)2(7)5(8)12-4/h9H,1H3

Upstream product

• 5118-06-9 methyl 3-hydroxy-2-thiophenecarboxylate 

Downstream Products

• 1047644-95-0 N-[2-amino-1-(phenylmethyl)ethyl]-4-bromo-3-(methyloxy)-5-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride 
• 1047644-93-8 1,1-dimethylethyl [2-({[4-bromo-3-(methyloxy)-5-(1-methyl-1H-pyrazol-5-yl)-2-thienyl]carbonyl}amino)-3-phenylpropyl]carbamate 
• 1047643-75-3 N-[2-amino-1-(phenylmethyl)ethyl]-4-bromo-3-(methyloxy)-5-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide 
• 1246405-92-4 methyl 5-(2-chlorophenyl)-4-(4-chlorophenyl)-3-hydroxy-thiophene-2-carboxylate 
• 1246405-84-4 methyl 4-bromo-5-(2-chlorophenyl)-3-methoxythiophene-2-carboxylate 
• 1246405-81-1 methyl 4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-3-methoxythiophene-2-carboxylate 
• 1246405-82-2 methyl 4-bromo-5-(2,4-dichlorophenyl)-3-methoxythiophene-2-carboxylate 
• 1246405-94-6 5-(2-Chlorophenyl)-4-(4-chlorophenyl)-3-[3-(tetrahydro-2H-pyran-2-yloxy)propoxy]thiophene-2-carboxylic acid 
• 1246405-93-5 Methyl 5-(2-chlorophenyl)-4-(4-chlorophenyl)-3-[3-(tetrahydro-2H-pyran-2-yloxy)propoxy]thiophene-2-carboxylate 
• 1246405-85-5 4-(4-Chlorophenyl)-5-(2,4-dichlorophenyl)-3-methoxythiophene-2-carboxylic acid 
• 1246405-83-3 Methyl 5-(2-chlorophenyl)-4-(4-chlorophenyl)-3-methoxy-thiophene-2-carboxylate 
• 175137-42-5 Methyl 4,5-dibromo-3-methoxythiophene-2-carboxylate 
• 1346685-15-1 C₂₀H₂₀O₄S 
• 1346685-11-7 2,5-bis(hydroxymethyl)-4-[4-(methyloxy)phenyl]-3-thienyl trifluoromethanesulfonate 

Relevant articles and documents

Organic compounds and their use as pharmaceuticals

Compounds of the following formula have pharmacutical properties: STR1 in which R1 and R2 independently are hydrogen, halo, nitro, amino, C2-5 acylamino, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylsulphonyl, N-substituted heterocyclyl, optionally substituted phenyl, optionally substituted phenylthio, optionally substituted phenylsulphonyl or optionally substituted phenylsulphonamido, or R1 and R2 together form a C3-5 alkylene bridge, R3 is C1-4 alkyl or C2-4 alkenyl, and X is (i) --(CH2)n N(R4)2 where each R4 independently is C1-4 alkyl, C2-4 alkenyl or optionally substituted C6 H5 CH2 --, and n is 1, 2 or 3, or (ii) a 5- to 8-membered alicyclic group containing one or two nitrogen atoms and directly attached to the amido nitrogen or attached by a C1-3 alkylene chain; and salts thereof.

N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof

The present invention is for compounds having the formula of N-1H-tetrazol-5-yl-2-thiophenecarboxamides, N-1H-tetrazol-5-yl-2-pyrrolecarboxamides, N-1H-tetrazol-5-yl-2-furancarboxamides or analogs of each of the carboxamides. The compounds are useful for the treatment of allergic or inflammatory conditions or diseases. Thus, pharmaceutical compositions and methods of use are also the invention. Processes of preparation for the compounds are also the invention.