Pyridazino[4,3-c]-isoquinolines having anti-anxiety activity
The present invention is directed to pyridazino[4,3-c]isoquinolines of Formula I STR1 wherein R represents methyl, phenyl or substituted phenyl groups, R 1 represents inter alia amino or substituted amino, alkoxy or cycloalkoxy groups, having pharmacologi
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(2008/06/13)
Benzodiazepine receptor binding and anticonflict activity in a series of 3,6-disubstituted pyridazino[4,3-c]isoquinolines devoid of anticonvulsant properties
A series of 3,6-disubstituted pyridazino [4,3-c]isoquinolines were synthesized and tested for their ability to inhibit the binding of [3H]diazepam to rat brain receptors in vitro. Compounds bearing a phenyl, 4-methyoxyphenyl, or methyl group at
Toja,Tarzia,Barone,Luzzani,Gallico
p. 1314 - 1319
(2007/10/02)
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