- Preparation method of cyproheptadine hydrochloride
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The invention discloses a preparation method of cyproheptadine hydrochloride. According to the invention, the existing preparation method of the cyproheptadine hydrochloride is integrally improved, sothat the whole synthesis step is greatly simplified; and the prepared cyproheptadine hydrochloride has higher purity and yield, and the preparation method reduces the use of organic solvents and hazardous chemicals, simplifies the operation steps, reduces the operation difficulty, not only reduces the cost but also lightens the environmental burden, and is more beneficial to large-scale industrial production.
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Paragraph 0049; 0054; 0056; 0061; 0063; 0068; 0070; 0075
(2019/11/14)
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- Water dispersion containing ultrafine particles of organic compounds
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A water-dispersible condensate of water-insoluble ultrafine particles of medicine or hormones having a particle size of at largest 4 μm prepared by the steps of heating the medicine or hormone in a vacuum vessel at a temperature of 30° C. higher than the boiling point and at a pressure between 0.01 Torr and 10 Torr to evaporate the medicine or hormone and condensing the medicine or hormone on a recovery plate to obtain the condensate.
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