cas 97352-64-2, N-(TERT-BUTOXYCARBONYL)GLYCINE-1-13C

Articles about 97352-64-2Total 5 be found

Direct biosynthetic cyclization of a distorted paracyclophane highlighted by double isotopic labelling of l-tyrosine
The biosynthesis of pyrrocidines, fungal PK-NRP compounds featuring a strained [9]paracyclophane, was investigated in Acremonium zeae. We used a synthetic l-tyrosine probe, labelled with oxygen 18 as a reporter of phenol reactivity and carbon 13 as a tracer of incorporation of this exogenous precursor. The (18O)phenolic oxygen was incorporated, suggesting that phenol behaves as a nucleophile during the formation of the bent aryl ether.
Ear, Alexandre,Amand, Séverine,Blanchard, Florent,Blond, Alain,Dubost, Lionel,Buisson, Didier,Nay, Bastien
p. 3662 - 3666
(2015)
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Application of Good's buffers to pH imaging using hyperpolarized 13C MRI
N-(2-Acetamido)-2-aminoethanesulfonic acid (ACES), one of Good's buffers, was applied to pH imaging using hyperpolarized 13C magnetic resonance spectroscopy. Rapid NMR- and MRI-based pH measurements were obtained by exploiting the sensitive pH-
p. 14119 - 14122
(2015)
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Synthesis and Spectroscopic Properties of 13C- and 15N-Labelled tert-Butoxycarbonylglycines
Three 13C-labelled bromoacetates have been reacted both with 15N-labelled and with unlabelled di-tert-butyl imidodicarbonate and the intermediates selectively deprotected to give the corresponding isotopomeric Boc-glycines for application in peptide synthesis.The products were characterized by 1H, 13C and 15N NMR and FT-IR spectroscopy.Isotope effects on chemical shifts and IR spectra for this set of compounds are tabulated.In addition, from three isotopomers 15N-labelled amides were also prepared.
Grehn, Leif,Pehk, Toenis,Ragnarsson, Ulf
p. 1107 - 1111
(2007/10/02)

Synthesis of 13C- and 15N-labelled tert-Butoxycarbonyl (Boc) Glycines and Glycine Amides as Precursors and Simple Models of Backbone-labelled Peptides
Boc-derivatives of the six 13C-labelled glycines with or without 15N have been prepared by a direct approach from the corresponding bromoacetates and three of them converted into 15N-labelled amides by an efficient procedure to give isotopomers with 2-4 adjacent 13C and 15N nuclei; their coupling constants have been recorded.
Grehn, Leif,Bondesson, Ulf,Pehk, Toenis,Ragnarsson, Ulf
p. 1332 - 1333
(2007/10/02)

β-LACTAM SYNTHESIS: CYCLIZATION VERSUS 1,2-ACYL MIGRATION-CYCLIZATION. THE MECHANISM OF THE 1,2-ACYL MIGRATION-CYCLIZATION
The cyclization of hydroxamate 1 unexpectedly afforded two isomeric β-lactams 2 and 3.The mechanism for the formation of 3 has been shown by carbon-13 labeling to involve a novel 1,2-acyl migration-cyclization process.
Godfrey, Jollie D.,Mueller, Richard H.,Langen, Derek J. Von
p. 2793 - 2796
(2007/10/02)