98-35-1

Basic information

• Product Name: 4-Amino-3-chlorobenzenesulfonic acid
• Synonyms: 4-AMINO-3-CHLOROBENZENESULFONIC ACID;3-chlorosulphanilic acid;2-CHLOROANILINE-4-SULFONIC ACID;o-CHLOROANILINE-p-SULFONOC ACID;3-Chloro-4-aminobenzenesulfonic acid;4-azanyl-3-chloro-benzenesulfonic acid
• CAS NO: 98-35-1
• Molecular Formula: C₆H₆ClNO₃S
• Molecular Weight: 207.63
• EINECS: 202-660-7
• Mol File: 98-35-1.mol

Chemical Properties

• Appearance: /
• Density: 1.642 g/cm³
• Refractive Index: 1.639
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Amino-3-chlorobenzenesulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-chlorobenzenesulfonic acid(98-35-1)
• EPA Substance Registry System: 4-Amino-3-chlorobenzenesulfonic acid(98-35-1)

Safety Data

• Hazardous Substances Data: 98-35-1(Hazardous Substances Data)

Usage

Uses

Used in Dye Industry:
4-Amino-3-chlorobenzenesulfonic acid is used as a chemical intermediate for the preparation of brown polysulfonamide dyes. Its presence in the dye synthesis process contributes to the formation of the desired color and properties of the final dye product, making it a valuable component in the dye manufacturing process.

InChI:InChI=1/C6H6ClNO3S/c7-5-3-4(12(9,10)11)1-2-6(5)8/h1-3H,8H2,(H,9,10,11)

Upstream product

• 95-51-2 o-chloroaniline 
• 95-50-1 1,2-dichloro-benzene 

Downstream Products

• 105548-19-4 4-(2-Acetylamino-4-diethylamino-phenylazo)-3-chloro-benzenesulfonic acid 
• 105547-81-7 4-(4-Amino-2-diethylamino-6-methyl-pyrimidin-5-ylazo)-3-chloro-benzenesulfonic acid 
• 105547-60-2 4-(5-Amino-3-methyl-1-phenyl-1H-pyrazol-4-ylazo)-3-chloro-benzenesulfonic acid 
• 105547-99-7 3-Chloro-4-(4,6-diamino-2-ethylsulfanyl-pyrimidin-5-ylazo)-benzenesulfonic acid 
• 874-18-0 2-chloro-4,6-dibromoaniline 

Relevant articles and documents

PEGYLATION PROCESS

The present invention relates to the attachment of a polyethylene glycol (PEG) moiety to a target substrate. Processes for such attachment will be hereinafter referred to as "PEGylation" of the substrate. In particular, the present invention relates to a process for direct covalent PEGylation of a substrate, comprising the reaction of a halogenated PEG with the substrate wherein the halogen of the halogenated PEG acts as a leaving group in the PEGylation reaction.

Sulfonation of arylamines Part 9 - Solid state synthesis of di-ortho ring substituted aminobenzenesulfonic acids

Di-ortho ring substituted arylammonium sulfates (Di-o-RSAS) have been prepared from the corresponding arylamines by treatment with conc. H2SO4 and characterized by elemental, gravimetric and spectral analyses. These sulfates yield the corresponding ring substituted aminobenzenesulfonic acids (RSABSA) when subjected to thermal energy. Non-isothermal gravimetric studies on di-o-RSAS support the formation of RSABSA. It is observed that most of the salts undergo transformation to acid in solid state via proton transfer reaction prior to sulfonation.

Process for the preparation of aminoaryl-sulphonic acids

Aminoaryl-sulphonic acids can be prepared by reaction of arylamines and sulphuric acid at elevated temperature and under pressure, where water formed and, where appropriate, water present as water of dilution, is left in the reaction mixture until the end of the reaction.

Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member

A reactive dye of the formula STR1 in which: F is a radical selected from the group consisting of metal-free or metal-containing monoazo or disazo dyes containing at least one --SO3 H group, anthraquinone dyes, sulfophthalocyanine dyes, formazan dyes, phenazine dyes, oxazine dyes and nitroaryl dyes, R is hydrogen, C1 -C4 alkyl which is unsubstituted or substituted with --COOH or --SO3 H, cyanoethyl, or hydroxyethyl, X is fluorine, chlorine, bromine, --SO3 H, phenylsulfonyl or C1 -C4 -alkylsulfonyl, p is 1 or 2 and A is a radical of the formula STR2 in which: Y is chlorine, bromine, fluorine, --OH, --OSO3 H, --O-acyl, --CN, --COOH, --COO--C1 -C4 -alkyl, --CONH2 or --SO2 --Z, the group designated "alk" is a straight or branched polymethylene radical having 2 to 6 carbon atoms, V is STR3 hydrogen or C1 -C4 -alkyl which is unsubstituted or substituted by C1 -C2 -alkoxy, carboxyl, sulfo, halogen or hydroxy, Z is β-halogenoethyl, vinyl or β-acetoxyethyl, or A is a radical of the formulae STR4 in all of which R' is C1-6 -alkyl or hydrogen, Z is as defined above, o is 0 to 6, and m is 2 to 6.

Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge

The invention relates to novel useful reactive dyes of the formula I STR1 in which: F is a radical selected from the group consisting of metal-free or metal-containing monoazo or disazo dyes containing at least one --SO3 H group, anthraquinone dyes, sulfophthalocyanine dyes, formazan dyes, phenazine dyes, oxanine dyes and nitroaryl dyes, R is hydrogen, C1 -C4 alkyl which is unsubstituted or substituted with --COOH or --SO3 H, cyanoethyl, or hydroxyethyl, X is fluorine, chlorine, bromine, --SO3 H, phenylsulfonyl or C1 -C4 -alkylsulfonyl, P is 1 or 2 and A is a radical of the formula STR2 in which: the groups designated "alk" are independently of each other straight or branched polymethylene radicals having 2 to 6 carbon atoms, and Z is β-halogenoethyl, vinyl, β-sulfatoethyl, β-thiosulfatoethyl or βacetoxyethyl.

Process for the preparation of aminoarylsulphonic acids in sulfolene solvent

Aromatic aminosulphonic acids which have a reduced content of discoloring by-products are obtained when aromatic amines are reacted with a sulphonating agent in a reaction medium at least some of which consists of tetramethylene sulphone.