95-50-1

Usage

Uses

Used in Industrial Applications:
o-Dichlorobenzene is used as an industrial solvent for its ability to dissolve a wide range of substances, making it a versatile component in the production of various chemicals and materials.
Used in Degreasing Processes:
o-Dichlorobenzene is used as a degreasant due to its effectiveness in removing grease and oils from surfaces, which is essential in cleaning and maintenance operations in various industries.
Used as a Chemical Intermediate:
o-Dichlorobenzene serves as a chemical intermediate in the synthesis of other compounds, contributing to the development of new products and materials in the chemical industry.
Used in Insecticides:
o-Dichlorobenzene is used in some insecticides for its ability to control pests, providing a means of protection against insects that can damage crops and transmit diseases.
However, it is important to note that exposure to o-Dichlorobenzene can occur through inhalation, skin contact, or ingestion, and may cause harmful health effects such as irritation of the eyes, skin, and throat, dizziness, and liver damage in higher concentrations. It is considered to be potentially carcinogenic by several health organizations, which highlights the need for proper handling and safety measures when using o-Dichlorobenzene.

Upstream product

• 17333-83-4 2-chlorobenzenediazonium 
• 694-80-4 2-bromo-1-chlorobenzene 
• 95-57-8 2-monochlorophenol 
• 577-19-5 2-nitrophenyl bromide 
• 89-90-7 2-chlorobenzenediazonium chloride 
• 108-90-7 chlorobenzene 
• 95-54-5 1,2-diamino-benzene 
• 95-51-2 o-chloroaniline 
• 528-29-0 1,2-Dinitrobenzene 
• 71-43-2 benzene 
• 274-09-9 Methylenedioxybenzene 
• 95-94-3 1,2,4,5-tetrachlorobenzene 
• 106-46-7 para-dichlorobenzene 
• 634-66-2 1,2,3,4,-tetrachlorobenzene 

Downstream Products

• 52192-59-3 (3,4-dichloro-phenyl)-[2]furyl ketone 
• 84-45-7 2,3-dichloro-anthraquinone 
• 52187-03-8 2-(3',4'-dichlorobenzoyl)benzoic acid 
• 860562-08-9 4,5-dichloro-2-(3,4-dichloro-benzoyl)-benzoic acid 
• 55441-63-9 3,9-dimethyluric acid 
• 855471-10-2 3,6-dichloro-2-(3,4-dichloro-benzoyl)-benzoic acid 
• 953-21-9 N-phenylcinnamaldimine 
• 15719-64-9 methylammonium carbonate 
• 114381-89-4 2-(dichloro-[1,3,5]triazin-2-yl)-phenol 
• 80542-40-1 N-cinnamylidene-p-anisidine 
• 6582-42-9 1-(3,4-dichlorophenyl)propan-1-one 
• 2642-63-9 3',4'-dichloroacetophenone 
• 6370-75-8 N,N'-bis-(5-benzoylamino-9,10-dioxo-9,10-dihydro-[1]anthryl)-oxalamide 
• 6284-79-3 3,4-dichlorobenzophenone 

Relevant academic research and scientific papers

Synthesis of Decorated Carbon Structures with Encapsulated Components by Low-Voltage Electric Discharge Treatment

Abstract: Polycondensation of complexes of chloromethanes with triphenylphosphine by the action of low-voltage electric discharges in the liquid phase gives nanosized solid products. The elemental composition involving the generation of element distribution maps (scanning electron microscopy–energy dispersive X?ray spectroscopy mapping) and the component composition (by direct evolved gas analysis–mass spectrometry) of the solid products have been studied. The elemental and component compositions of the result-ing structures vary widely depending on the chlorine content in the substrate and on the amount of triphenylphosphine taken. Thermal desorption analysis revealed abnormal behavior of HCl and benzene present in the solid products. In thermal desorption spectra, these components appear at an uncharacteristically high temperature. The observed anomaly in the behavior of HCl is due to HCl binding into a complex of the solid anion HCI-2 with triphenyl(chloromethyl)phosphonium chloride, which requires a relatively high temperature (up to 800 K) to decompose. The abnormal behavior of benzene is associated with its encapsulated state in nanostructures. The appearance of benzene begins at 650 K and continues up to temperatures above 1300?K.

A method for producing o-dichlorobenzene by one-pot method of o-nitrochlorobenzene as raw material

The present invention relates to a method for producing o-dichlorobenzene by a pot method of producing o-nitrochlorobenzene as raw material. Based on a continuous reactor, the continuous reactor is a reaction device connected to the reaction kettle and the catalyst packing tower, the opening of the reaction kettle is directly connected to the inlet at the bottom of the tower, the reaction kettle is provided with a feeding port and an aeration port, the catalyst packing tower top is provided with a gas inlet outlet, o-nitrochlorobenzene and continuously passed chlorine as raw material, with peroxide and azode complex catalyst as the catalyst, at 225-255 ° C, 0.11- Under the condition of 0.15Mpa, the denitrochlorination reaction was carried out in a continuous reactor to generate o-dichlorobenzene and tail gas nitrate chloride, and o-dichlorobenzene was elicitated from the top outlet of the tower along with the tail gas nitrate chloride, and the liquid o-dichlorobenzene, o-dichlorobenzene and tail gas nitroyl chloride were condensed to a residence time of 5-20min in the catalyst packing column. The high-temperature, short-term synthesis of o-dichlorobenzene, energy consumption is significantly reduced, there are few by-products, no isomers, and the conversion rate is high, up to 95%.

Facile Synthesis of a Fully Fused, Three-Dimensional ?-Conjugated Archimedean Cage with Magnetically Shielded Cavity

The synthesis of molecular cages consisting of fully fused, ?-conjugated rings is rare due to synthetic challenges including preorganization, large strain, and poor solubility. Herein, we report such an example in which a tris-2-aminobenzophenone precursor undergoes acid-mediated self-condensation to form a truncated tetrahedron, one of the 13 Archimedean solids. Formation of eight-membered [1,5]diazocine rings provides preorganization and releases the strain while still maintains weak ?-conjugation of the backbone. Thorough characterizations were performed by X-ray, NMR, and UV-vis analysis, assisted by theoretical calculations. The cage exhibits a rigid backbone structure with a well-defined cavity that confines a magnetically shielded environment. The solvent molecule, o-dichlorobenzene, is precisely encapsulated in the cavity at a 1:1 ratio with multiple ?···?, C-H···?, and halogen···πinteractions with the cage skeleton, implying its template effect for the cage closing reaction. Our synthetic strategy opens the opportunity to access more complex, fully fused, three-dimensional ?-conjugated cages.

The graphite-catalyzed: ipso -functionalization of arylboronic acids in an aqueous medium: metal-free access to phenols, anilines, nitroarenes, and haloarenes

An efficient, metal-free, and sustainable strategy has been described for the ipso-functionalization of phenylboronic acids using air as an oxidant in an aqueous medium. A range of carbon materials has been tested as carbocatalysts. To our surprise, graphite was found to be the best catalyst in terms of the turnover frequency. A broad range of valuable substituted aromatic compounds, i.e., phenols, anilines, nitroarenes, and haloarenes, has been prepared via the functionalization of the C-B bond into C-N, C-O, and many other C-X bonds. The vital role of the aromatic π-conjugation system of graphite in this protocol has been established and was observed via numerous analytic techniques. The heterogeneous nature of graphite facilitates the high recyclability of the carbocatalyst. This effective and easy system provides a multipurpose approach for the production of valuable substituted aromatic compounds without using any metals, ligands, bases, or harsh oxidants.

NUCLEANT ENHANCING NUCLEATION OF A PROTEIN CRYSTAL AND PROTEIN CRYSTALLIZATION METHOD WITH THE SAME

A balanced-lattice-ledge nucleant having ledge inducing local densification of proteins and a balanced-lattice inducing self-organized crystal packing. Using this balanced-lattice-ledge nucleant enhances nucleation of protein crystals.

Dehydroxyalkylative halogenation of C(aryl)-C bonds of aryl alcohols

We herein report Cu mediated side-directed dehydroxyalkylative halogenation of aryl alcohols. C(aryl)-C bonds of aryl alcohols were effectively cleaved, affording the corresponding aryl chlorides, bromides and iodides in excellent yields. Aryl alcohols could serve as both aromatic electrophilic and radical synthetic equivalents during the reaction.

Amplification of Trichloroisocyanuric Acid (TCCA) Reactivity for Chlorination of Arenes and Heteroarenes via Catalytic Organic Dye Activation

Heteroarenes and arenes that contain electron-withdrawing groups are chlorinated in good to excellent yields (scalable to gram scale) using trichloroisocyanuric acid (TCCA) and catalytic Brilliant Green (BG). Visible-light activation of BG serves to amplify the electrophilic nature of TCCA, providing a mild alternative approach to acid-promoted chlorination of deactivated (hetero)aromatic substrates. The utility of the TCCA/BG system is demonstrated through comparison to other chlorinating reagents and by the chlorination of pharmaceuticals including caffeine, lidocaine, and phenazone.

Chiral fluorescent compound based on cyclophane alkane framework and preparation method and application of compound

The invention relates to a chiral fluorescent compound based on a cyclophane alkane framework and a preparation method and application of the compound. By using the rigid framework structure of cyclophane alkane, the chirality of the cyclophane alkane can be well kept under the excitation state, and accordingly high asymmetry factors are obtained. By changing R2 and R3 substituent groups, the luminescence section, CPL intensity and luminescence intensity can be regulated and controlled. By changing R1 substituent groups, a thermal-activation delayed fluorescence material is obtained. Phenazinemolecules based on the cyclophane alkane have a good circularly polarized luminescence characteristic and have potential application in the aspects of 3D optical display, information storage and transmission, confidential information recording, optoelectronic devices and even asymmetry photochemical synthesis.

Method for synthesizing dichlorobenzene

The invention provides a method for synthesizing dichlorobenzene, and the method comprises the following steps: taking trichlorobenzene as a substrate, adding dimethyl sulfoxide (DMSO), an aqueous solution of M(OH)n and a catalyst to form a mixture; stirring and heating the mixture; and contacting hydrogen with the mixture and heating for reaction to obtain the dichlorobenzene; the pH value of theaqueous solution of M(OH)n is great than 7, M is an alkali metal or alkaline earth metal, and n is a positive integer; and the catalyst is a metal catalyst or a metal supported catalyst.

Selective Hydrogenations and Dechlorinations in Water Mediated by Anionic Surfactant-Stabilized Pd Nanoparticles

We report a facile, inexpensive, and green method for the preparation of Pd nanoparticles in aqueous medium stabilized by anionic sulfonated surfactants sodium 1-dodecanesulfonate 1a, sodium dodecylbenzenesulfonate 1b, dioctyl sulfosuccinate sodium salt 1c, and poly(ethylene glycol) 4-nonylphenyl-3-sulfopropyl ether potassium salt 1d simply obtained by stirring aqueous solutions of Pd(OAc)2 with the commercial anionic surfactants further treated under hydrogen atmosphere for variable amounts of time. The aqueous Pd nanoparticle solutions were tested in the selective hydrogenation reactions of aryl-alcohols, -aldehydes, and -ketones, leading to complete conversion to the deoxygenated products even in the absence of strong Br?nsted acids in the reduction of aromatic aldehydes and ketones, in the controlled semihydrogenation of alkynes leading to alkenes, and in the efficient hydrodechlorination of aromatic substrates. In all cases, the micellar media were crucial for stabilizing the metal nanoparticles, dissolving substrates, steering product selectivity, and enabling recycling. What is interesting is also that a benchmark catalyst like Pd/C can often be surpassed in activity and/or selectivity in the reactions tested by simply switching to the appropriate commercially available surfactant, thereby providing an easy to use, flexible, and practical catalytic system capable of efficiently addressing a variety of synthetically significant hydrogenation reactions.