cas 98434-06-1, 5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID | Articles data ｜lookchem

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98434-06-1

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ATF6 INHIBITORS AND USES THEREOF
Compounds as inhibitors of Activating Transcription Factor 6 (ATF6) are provided. The compounds may find use as therapeutic agents for the treatment of diseases or disorders mediated by ATF6 and may find particular use in the treatment of viral infections, neurodegenerative diseases, vascular diseases, or cancer.
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(2019/10/29)

PHARMACEUTICAL COMPOSITION FOR PREVENTINTION AND TREATMENT OF RESTENOSIS COMPRISING ISOXAZOLE DERIVATIVES
There is provided a pharmaceutical composition for prevention and treatment of restenosis comprising isoxazole derivatives. The pharmaceutical composition includes a therapeutic effective amount of isoxazole derivatives represented by Formula 1 or pharmaceutically available salts thereof. The pharmaceutical composition may be useful to prevent and treat vascular restenosis since the pharmaceutical composition shows an anti-restenosis activity and accelerates the re-endothelization.
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Page/Page column 18

(2009/03/07)

ISOXAZOLE DERIVATIVES AND USE THEREOF
Disclosed herein are isoxazole derivatives and uses thereof. Serving as agonists of Wnt, the isoxazole derivatives activate Wnt/beta-catenin signaling and thus can be used in the treatment and prevention of diseases related to the signal transduction. Also, pharmaceutically acceptable salts of the isoxazole derivatives are disclosed
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Page/Page column 12

(2009/05/28)

ISOXAZOLE DERIVATIVES AND USE THEREOF
Disclosed herein are isoxazole derivaties and uses thereof. Serving as agonists of Wnt, the isoxazole derivatives activate Wnt/β-catenin signaling and thus can be used in the treatment and prevention of diseases related to the signal transduction. Also, pharmaceutically acceptable salts of the isoxazole derivatives are disclosed.
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Page/Page column 36

(2010/11/28)

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909089-13-0
SKL2001

Chemical Properties

Melting Point: 151 °C
Boiling Point: 418.4 °C at 760 mmHg
Flash Point:206.8 °C
Density: 1.42 g/cm³
Storage Temp.:Sealed in dry,Store in freezer, under -20°C
Vapor Pressure: 9.5E-08mmHg at 25°C
Refractive Index: 1.555
PKA: 3.33±0.10(Predicted)
PSA: 76.47000
LogP: 1.63280

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