98434-06-1

Basic information

• Product Name: 5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID
• Synonyms: 5-(2-furyl)-3-isoxazolecarboxylic acid;5-(2-furanyl)-3-isoxazolecarboxylic acid;TIMTEC-BB SBB007153;5-FURAN-2-YL-ISOXAZOLE-3-CARBOXYLIC ACID;AKOS B022856;AKOS PAO-1387;AKOS BBS-00006855;5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID
• CAS NO: 98434-06-1
• Molecular Formula: C₈H₅NO₄
• Molecular Weight: 179.13
• Product Categories: Oxazole&Isoxazole
• Mol File: 98434-06-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 151 °C
• Boiling Point: 418.4 °C at 760 mmHg
• Flash Point: 206.8 °C
• Appearance: /
• Density: 1.42 g/cm³
• Vapor Pressure: 9.5E-08mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 3.33±0.10(Predicted)
• CAS DataBase Reference: 5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID(98434-06-1)
• EPA Substance Registry System: 5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID(98434-06-1)

Safety Data

• Statements: 36/37/38
• Safety Statements: 22-26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 98434-06-1(Hazardous Substances Data)

Usage

General Description

5-(2-Furyl)isoxazole-3-carboxylic acid is a chemical compound belonging to the isoxazole carboxylic acid family. It is composed of a central isoxazole ring with a furan group at the 2-position and a carboxylic acid group at the 3-position. 5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID has potential applications in the field of pharmaceuticals and organic synthesis due to its unique structure and reactivity. It is also used in the preparation of various derivatives and analogs for medicinal and agrochemical purposes. The presence of the furan group and carboxylic acid functionality makes it a suitable candidate for further modification and diversification to generate new compounds with desired properties and activities.

InChI:InChI=1/C8H5NO4/c10-8(11)5-4-7(13-9-5)6-2-1-3-12-6/h1-4H,(H,10,11)

Upstream product

• 36983-35-4 ethyl 4-(furan-2-yl)-2,4-dioxobutyrate 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 33545-40-3 5-furan-2-yl-isoxazole-3-carboxylic acid ethyl ester 

Downstream Products

• 1266788-01-5 5-furan-2-yl-isoxazole-3-carboxylic acid [3-((RS)-5-amino-3-methyl-3,6-dihydro-2H-[1,4]oxazin-3-yl)-4-fluoro-phenyl]-amide 

Relevant articles and documents

ATF6 INHIBITORS AND USES THEREOF

Compounds as inhibitors of Activating Transcription Factor 6 (ATF6) are provided. The compounds may find use as therapeutic agents for the treatment of diseases or disorders mediated by ATF6 and may find particular use in the treatment of viral infections, neurodegenerative diseases, vascular diseases, or cancer.

ISOXAZOLE DERIVATIVES AND USE THEREOF

Disclosed herein are isoxazole derivatives and uses thereof. Serving as agonists of Wnt, the isoxazole derivatives activate Wnt/beta-catenin signaling and thus can be used in the treatment and prevention of diseases related to the signal transduction. Also, pharmaceutically acceptable salts of the isoxazole derivatives are disclosed