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Thieno[2,3-b]pyridine-5-carboxylic acid, 6,7-dihydro-4-hydroxy-6-oxo-, ethyl ester is a complex chemical compound belonging to the thieno[2,3-b]pyridine derivatives class. It is characterized by its potential therapeutic properties and is commonly used in the pharmaceutical industry.

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  • ethyl 4-hydroxy-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carboxylate

    Cas No: 99429-68-2

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  • Thieno[2,3-b]pyridine-5-carboxylic acid, 6,7-dihydro-4-hydroxy-6-oxo-, ethyl ester

    Cas No: 99429-68-2

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  • 99429-68-2 Structure
  • Basic information

    1. Product Name: Thieno[2,3-b]pyridine-5-carboxylic acid, 6,7-dihydro-4-hydroxy-6-oxo-, ethyl ester
    2. Synonyms: Thieno[2,3-b]pyridine-5-carboxylic acid, 6,7-dihydro-4-hydroxy-6-oxo-, ethyl ester;Ethyl 4-hydroxy-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carboxylate
    3. CAS NO:99429-68-2
    4. Molecular Formula: C10H9NO4S
    5. Molecular Weight: 239.24776
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 99429-68-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 475.7±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.507±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
    8. Solubility: N/A
    9. PKA: 4.50±1.00(Predicted)
    10. CAS DataBase Reference: Thieno[2,3-b]pyridine-5-carboxylic acid, 6,7-dihydro-4-hydroxy-6-oxo-, ethyl ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: Thieno[2,3-b]pyridine-5-carboxylic acid, 6,7-dihydro-4-hydroxy-6-oxo-, ethyl ester(99429-68-2)
    12. EPA Substance Registry System: Thieno[2,3-b]pyridine-5-carboxylic acid, 6,7-dihydro-4-hydroxy-6-oxo-, ethyl ester(99429-68-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 99429-68-2(Hazardous Substances Data)

99429-68-2 Usage

Uses

Used in Pharmaceutical Industry:
Thieno[2,3-b]pyridine-5-carboxylic acid, 6,7-dihydro-4-hydroxy-6-oxo-, ethyl ester is used as a therapeutic agent for its anti-inflammatory, analgesic, and anti-cancer activities. Its ethyl ester form enhances its solubility and ease of administration, potentially improving its bioavailability and effectiveness in various therapeutic applications.
Further research is required to fully understand and harness the potential benefits of this compound, as its complex molecular structure and diverse applications necessitate a deeper understanding of its mechanisms of action and safety profile.

Check Digit Verification of cas no

The CAS Registry Mumber 99429-68-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,4,2 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 99429-68:
(7*9)+(6*9)+(5*4)+(4*2)+(3*9)+(2*6)+(1*8)=192
192 % 10 = 2
So 99429-68-2 is a valid CAS Registry Number.

99429-68-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4-hydroxy-6-oxo-7H-thieno[2,3-b]pyridine-5-carboxylate

1.2 Other means of identification

Product number -
Other names Ethyl 4-hydroxy-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:99429-68-2 SDS

99429-68-2Relevant articles and documents

PROLYL HYDROXYLASE INHIBITORS

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Page/Page column 14, (2008/06/13)

The invention described herein relates to certain bicyclic heteroaromatic N-substituted glycine derivatives of formula (I ) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme

THIENOPYRIDINONE DERIVATIVES AS MACROPHAGE MIGRATION INHIBITORY FACTOR INHIBITORS

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Page/Page column 62-63, (2010/11/24)

Inhibitors of macrophage migration inhibitory factor having a thienopyridinone backbone are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with macrophage migration inhibitory factor activity. The inhibitors of macrophage migration inhibitory factor have the following structures formula (I), (II), (III) including forms such as stereoisomers, free forms, pharmaceutically acceptable salts or esters thereof, solvates, or combinations of such forms, wherein n, R1, R2, R3, X, and Y are as defined herein. Compositions comprising an inhibitor of macrophage migration inhibitory factor in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.

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