100101-45-9

Basic information

• Product Name: (2'S)-(4E)-2'-hydroxy-oct-4'-enoic acid (1R,2S,5R)-8-phenylmenthyl ester
• Synonyms: (2'S)-(4E)-2'-hydroxy-oct-4'-enoic acid (1R,2S,5R)-8-phenylmenthyl ester
• CAS NO: 100101-45-9
• Molecular Weight: 372.548
• Mol File: 100101-45-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2'S)-(4E)-2'-hydroxy-oct-4'-enoic acid (1R,2S,5R)-8-phenylmenthyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2'S)-(4E)-2'-hydroxy-oct-4'-enoic acid (1R,2S,5R)-8-phenylmenthyl ester(100101-45-9)
• EPA Substance Registry System: (2'S)-(4E)-2'-hydroxy-oct-4'-enoic acid (1R,2S,5R)-8-phenylmenthyl ester(100101-45-9)

Safety Data

• Hazardous Substances Data: 100101-45-9(Hazardous Substances Data)

Upstream product

• 592-41-6 1-hexene 
• 84312-20-9 (1R,3R,4S)-8-phenylmenthyl glyoxylate 
• 72526-00-2 (-)-8-phenylmenthyl acrylate 
• 104197-95-7 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl nitrooxyacetate 
• 80595-59-1 bromoacetic acid (-)-8-phenylmenthol ester 
• 65253-04-5 (-)-8-phenylmenthol 

Downstream Products

• 108793-98-2 (-)-8-phenylmenthyl (2S)-2-hydroxyoctanoate 

Relevant articles and documents

Synthesis of chiral 4-substituted 2-hydroxypent-4-enoic acid derivatives via diastereoselective ene reaction promoted by ZnBr2

The diastereoselective carbonyl-ene reaction of various 1,1-disubstituted olefins with the chiral derivatives of glyoxylic acid, with Oppolzer's sultam 1a and 8-phenylmenthol 1b auxiliaries, was studied. The reaction proceeds effectively under undemanding

ASYMMETRIC INDUCTION IN THE ENE REACTION OF GLYOXYLATE ESTERS OF 8-PHENYLMENTHOL

We recently communicated (J.K.Whitesell, A.Bhattacharya, D.A.Aguilar and K.Henke, J.Chem.Soc.Chem.Commun. 989 (1982)) a highly efficient and effective method for the control of absolute stereochemistry through asymmetric induction in the ene reaction the chiral glyoxylate 1 with alkenes.We now have accumulated sufficient information on this process in terms of both its mechanistic details as well as its scope and applicability to a variety of situations that warrants a more complete presentation of these reactions.