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1002304-34-8

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1002304-34-8 Usage

Definition

ChEBI: A member of the class of quinolines that is 7-methoxyquinoline substituted at position 4 by a (6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy group. AMG exhibits antitumour activity, particularly in prostate cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 1002304-34-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,2,3,0 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1002304-34:
(9*1)+(8*0)+(7*0)+(6*2)+(5*3)+(4*0)+(3*4)+(2*3)+(1*4)=58
58 % 10 = 8
So 1002304-34-8 is a valid CAS Registry Number.
InChI:InChI=1S/C22H17N5O2/c1-28-16-7-8-17-19(13-16)23-12-11-20(17)29-14-22-25-24-21-10-9-18(26-27(21)22)15-5-3-2-4-6-15/h2-13H,14H2,1H3

1002304-34-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-methoxy-4-[(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline

1.2 Other means of identification

Product number -
Other names 7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1002304-34-8 SDS

1002304-34-8Downstream Products

1002304-34-8Relevant articles and documents

Discovery and optimization of triazolopyridazines as potent and selective inhibitors of the c-Met kinase

Albrecht, Brian K.,Harmange, Jean-Christophe,Bauer, David,Berry, Loren,Bode, Christiane,Boezio, Alessandro A.,Chen, April,Choquette, Deborah,Dussault, Isabelle,Fridrich, Cary,Hirai, Satoko,Hoffman, Doug,Larrow, Jay F.,Kaplan-Lefko, Paula,Lin, Jasmine,Lohman, Julia,Long, Alexander M.,Moriguchi, Jodi,O'Connor, Anne,Potashman, Michele H.,Reese, Monica,Rex, Karen,Siegmund, Aaron,Shah, Kavita,Shimanovich, Roman,Springer, Stephanie K.,Teffera, Yohannes,Yang, Yajing,Zhang, Yihong,Bellon, Steven F.

supporting information; experimental part, p. 2879 - 2882 (2009/05/30)

Tumorigenesis is a multistep process in which oncogenes play a key role in tumor formation, growth, and maintenance. MET was discovered as an oncogene that is activated by its ligand, hepatocyte growth factor. Deregulated signaling in the c-Met pathway ha

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