100367-38-2

Basic information

• Product Name: no
• Synonyms: 3-AMino-5-broMophenol;3-Amino-5-bromophenol 97%;3-Bromo-5-hydroxyaniline;3-broMo-5-aMinophenol;3-Amino-5-bromophenol97%
• CAS NO: 100367-38-2
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188.02194
• Mol File: 100367-38-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: no(CAS DataBase Reference)
• NIST Chemistry Reference: no(100367-38-2)
• EPA Substance Registry System: no(100367-38-2)

Safety Data

• Hazardous Substances Data: 100367-38-2(Hazardous Substances Data)

Usage

General Description

3-Amino-5-bromophenol is a chemical compound with the molecular formula C6H6BrNO. It is an amino-phenol derivative, meaning it contains a phenolic and an amino group. 3-Amino-5-bromophenol is used in various industries, including pharmaceuticals, dyes, and organic synthesis. It is a building block for the synthesis of various organic compounds, and it is also used as an intermediate in the production of azo dyes. 3-Amino-5-bromophenol is a white to light brown crystalline solid with a melting point of around 150-153°C, and its chemical structure makes it reactive and able to participate in a variety of chemical reactions. Its uses and reactivity make it an important compound in the chemical and pharmaceutical industries.

Upstream product

• 16618-68-1 3-bromo-5-methoxyaminobenzene 
• 116632-23-6 3-bromo-5-nitro-phenol 
• 121-88-0 5-Nitro-2-aminophenol 

Downstream Products

• 1085526-12-0 3-bromo-5-[[6-[[(R)-methyloxidophenyl-λ4-sulphanylidene]amino]quinolin-4-yl]amino]phenol 

Relevant articles and documents

Discovery of meta-amido bromophenols as new antitubercular agents

A series of meta-amido bromophenol derivatives were designed and synthesized. The compounds were found to potently inhibit the growth of Mycobacterium tuberculosis H37Ra. They also exhibited moderate inhibitory activity against Mycobacterium tuberculosis H37Rv and multidrug-resistant strains. The compounds did not show inhibitory activity against normal Gram-positive and Gram-negative bacteria. Moderate cytotoxicities and good metabolic stability were observed for the selected compounds. The results demonstrated meta-amido bromophenols as a new class of antitubercular agents with good potentials.

TRPV4 ANTAGONISTS

The present invention relates to quinoline analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.