16618-68-1

Basic information

• Product Name: 3-bromo-5-methoxyaniline
• Synonyms: 3-bromo-5-methoxyaniline;3-Bromo-5-methoxyaniline 98%;3-Amino-5-bromoanisole, 5-Bromo-m-anisidine;BenzenaMine, 3-broMo-5-Methoxy-;3-broMo-5-MethoxyaMinobenzene;3-BroMo-5-Methoxy-phenylaMine;3-bromo-5-methoxybenzenamine;3-Bromo-5-methyloxybenzenamine
• CAS NO: 16618-68-1
• Molecular Formula: C₇H₈BrNO
• Molecular Weight: 202
• Mol File: 16618-68-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 285.8±20.0℃ (760 Torr)
• Flash Point: 126.7±21.8℃
• Appearance: /
• Density: 1.531±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 3.10±0.10(Predicted)
• CAS DataBase Reference: 3-bromo-5-methoxyaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-5-methoxyaniline(16618-68-1)
• EPA Substance Registry System: 3-bromo-5-methoxyaniline(16618-68-1)

Safety Data

• Hazardous Substances Data: 16618-68-1(Hazardous Substances Data)

Usage

General Description

3-bromo-5-methoxyaniline is a chemical compound with the molecular formula C7H8BrNO and a molecular weight of 206.05 g/mol. It is a substituted aniline, with a bromine atom and a methoxy group attached to the benzene ring. 3-bromo-5-methoxyaniline is commonly used in organic synthesis and pharmaceutical research. It has been studied for its potential use in the development of new drugs and as a building block in the production of various pharmaceutical compounds. 3-bromo-5-methoxyaniline is known for its ability to participate in various chemical reactions, making it a valuable intermediate in the synthesis of complex organic molecules. Due to its potential applications in medicinal chemistry, this compound is of interest to researchers in the pharmaceutical and biotechnology industries.

Upstream product

• 18242-39-2 3,5-dinitrobromobenzene 
• 99-65-0 meta-dinitrobenzene 
• 16618-67-0 3-bromo-5-nitroanisole 

Downstream Products

• 855400-66-7 3-bromo-5-methoxyphenol 
• 915412-18-9 1-bromo-3-iodo-5-methoxybenzene 
• 938061-52-0 (3-Bromo-5-methoxy-phenyl)-(2,2-diethoxy-ethyl)-amine 
• 1610628-06-2 N-(3-bromo-5-methoxyphenyl)-3-methoxyacrylamide 
• 1261677-80-8 7-bromo-5-hydroxy-quinoline 
• 1332626-17-1 N,N-diallyl-3-bromo-5-methoxyaniline 
• 1332626-38-6 (2E,4R,6E,8E,10S,11R,12S,14R)-ethyl 15-(3-amino-5-methoxyphenyl)-11,12-dimethoxy-2,4,8,10,14-pentamethylpentadeca-2,6,8-trienoate 
• 1332626-36-4 (2E,4S,6E,8E,10S,11R,12S,14R)-ethyl 15-(3-amino-5-methoxyphenyl)-11,12-dimethoxy-2,4,8,10,14-pentamethylpentadeca-2,6,8-trienoate 
• 1332626-23-9 (2E,6E,8E,10S,11R,12S,14R)-ethyl 15-(3-amino-5-methoxyphenyl)-11,12-dimethoxy-2,8,10,14-tetramethylpentadeca-2,6,8-trienoate 
• 1332626-22-8 3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline 

Relevant articles and documents

TEAD INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

M-di-substituted phenol compound as well as preparation method thereof and application of tubercle bacillus resistance

The invention provides an m-di-substituted phenol compound with a general formula (I) as well as a preparation method and application thereof. The m-di-substituted phenol compound provided by the invention has a novel tubercle bacillus resistance drug parent nucleus structure and excellent tubercle bacillus resistance activity and especially has very strong inhibition activity on a drug-resistantvariant tubercle bacillus strain. The invention further provides the preparation method of the m-di-substituted phenol compound; the preparation method has the advantages that raw materials are cheapand easy to obtain, a high-toxicity and high-pollution reagent are not needed, reaction steps are simple and industrialized production can be realized; the m-di-substituted phenol compound has a goodmedicinal prospect.

Metal-Free Reduction of Aromatic Nitro Compounds to Aromatic Amines with B2pin2 in Isopropanol

A metal-free reduction of aromatic nitro compounds to the corresponding amines has been achieved by a combination of B2pin2 and KOtBu in isopropanol. A series of nitro compounds containing various reducible functional groups were chemoselectively reduced in good to excellent yields.