1003887-67-9 Usage
Description
(S)-1-[4-(trifluoromethyl)phenyl]propylamine, with the molecular formula C10H13F3N, is an amine derivative characterized by a propyl chain and a trifluoromethylphenyl group. It is a member of the aralkylamines class, which are amines containing an aromatic group attached to an alkyl group. This chemical compound holds potential for various applications in the pharmaceutical and chemical industries, including the synthesis of other organic compounds and the development of biologically active molecules. Its unique chemical and pharmacological properties also make it a candidate for research and development.
Uses
Used in Pharmaceutical Industry:
(S)-1-[4-(trifluoromethyl)phenyl]propylamine is used as a building block for the development of biologically active molecules due to its unique chemical structure and properties. It can be utilized in the synthesis of pharmaceutical compounds that target specific receptors or enzymes in the body, potentially leading to the creation of new drugs for various medical conditions.
Used in Chemical Industry:
In the chemical industry, (S)-1-[4-(trifluoromethyl)phenyl]propylamine serves as a key intermediate in the synthesis of other organic compounds. Its trifluoromethylphenyl group and propyl chain can be further modified or used to create a variety of chemical products, such as agrochemicals, dyes, and specialty chemicals.
Used in Research and Development:
(S)-1-[4-(trifluoromethyl)phenyl]propylamine is used as a research compound for studying its unique chemical and pharmacological properties. This can lead to a better understanding of its potential applications in various fields, such as drug discovery, materials science, and chemical engineering.
Check Digit Verification of cas no
The CAS Registry Mumber 1003887-67-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,3,8,8 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1003887-67:
(9*1)+(8*0)+(7*0)+(6*3)+(5*8)+(4*8)+(3*7)+(2*6)+(1*7)=139
139 % 10 = 9
So 1003887-67-9 is a valid CAS Registry Number.
1003887-67-9Relevant articles and documents
Stereoselective amination of racemic sec-alcohols through sequential application of laccases and transaminases
Martínez-Montero, Lía,Gotor, Vicente,Gotor-Fernández, Vicente,Lavandera, Iván
, p. 474 - 480 (2017/06/23)
A one-pot/two-step bienzymatic asymmetric amination of secondary alcohols is disclosed. The approach is based on a sequential strategy involving the use of a laccase/TEMPO catalytic system for the oxidation of alcohols into ketone intermediates, and their following transformation into optically enriched amines by using transaminases. Individual optimizations of the oxidation and biotransamination reactions have been carried out, studying later their applicability in a concurrent process. Therefore, 17 racemic (hetero) aromatic sec-alcohols with different substitutions in the aromatic ring have been converted into enantioenriched amines with good to excellent selectivities (90-99% ee) and conversion values (67-99%). The scalability of the process was also demonstrated when two different amine donors were used in the transamination step, such as isopropylamine and cis-2-buten-1,4-diamine. Satisfyingly, both sacrificial amine donors can shift the equilibrium toward the amine formation, leading to the corresponding isolated enantioenriched amines with good to excellent results.
