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IMidazo[1,2-a]pyridine, 8-Methoxy, also known as 8-Methoxy imidazo[1,2-a]pyridine, is a heterocyclic chemical compound with the molecular formula C8H8N2O. It features a pyridine ring fused to an imidazole ring, with an 8-methoxy group attached to the imidazole ring, providing the compound with its distinctive structure. IMidazo[1,2-a]pyridine, 8-Methoxy is widely utilized in medicinal chemistry research for the development of potential drug candidates, particularly in neuroscience and cancer research. Its unique structure and properties make it a valuable building block for the synthesis of various biologically active compounds. Furthermore, 8-Methoxy imidazo[1,2-a]pyridine has been studied for its potential use as a fluorescent probe and as an intermediate in the synthesis of pharmaceuticals.

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  • 100592-04-9 Structure
  • Basic information

    1. Product Name: IMidazo[1,2-a]pyridine, 8-Methoxy
    2. Synonyms: IMidazo[1,2-a]pyridine, 8-Methoxy;8-Methoxy-iMidazo[1,2-a]pyridine
    3. CAS NO:100592-04-9
    4. Molecular Formula: C8H8N2O
    5. Molecular Weight: 148.16192
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 100592-04-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.18±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 5.89±0.50(Predicted)
    10. CAS DataBase Reference: IMidazo[1,2-a]pyridine, 8-Methoxy(CAS DataBase Reference)
    11. NIST Chemistry Reference: IMidazo[1,2-a]pyridine, 8-Methoxy(100592-04-9)
    12. EPA Substance Registry System: IMidazo[1,2-a]pyridine, 8-Methoxy(100592-04-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 100592-04-9(Hazardous Substances Data)

100592-04-9 Usage

Uses

Used in Medicinal Chemistry Research:
IMidazo[1,2-a]pyridine, 8-Methoxy is used as a building block for the development of potential drug candidates due to its unique structure and properties. It is particularly valuable in the fields of neuroscience and cancer research, where its heterocyclic nature contributes to the creation of biologically active compounds.
Used in Fluorescent Probe Development:
IMidazo[1,2-a]pyridine, 8-Methoxy is used as a potential fluorescent probe in various scientific applications. Its fluorescent properties allow it to be utilized in the detection and imaging of specific biological targets, making it a valuable tool in research and diagnostics.
Used in Pharmaceutical Synthesis:
IMidazo[1,2-a]pyridine, 8-Methoxy serves as an intermediate in the synthesis of pharmaceuticals. Its presence in the molecular structure of certain drugs aids in the development of new therapeutic agents, enhancing the efficacy and selectivity of these medications.
Used in Chemical Synthesis Industry:
In the chemical synthesis industry, IMidazo[1,2-a]pyridine, 8-Methoxy is used as a key intermediate for the production of various organic compounds. Its unique structure allows for the creation of a wide range of chemical entities, contributing to the advancement of the chemical synthesis field.
Used in Research and Development:
IMidazo[1,2-a]pyridine, 8-Methoxy is used in research and development for the exploration of its potential applications in various scientific and industrial areas. Its unique properties and structure make it a promising candidate for further investigation and utilization in innovative applications.

Check Digit Verification of cas no

The CAS Registry Mumber 100592-04-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,5,9 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 100592-04:
(8*1)+(7*0)+(6*0)+(5*5)+(4*9)+(3*2)+(2*0)+(1*4)=79
79 % 10 = 9
So 100592-04-9 is a valid CAS Registry Number.

100592-04-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-methoxyimidazo[1,2-a]pyridine

1.2 Other means of identification

Product number -
Other names methoxy-8 imidazo<1,2-a>pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100592-04-9 SDS

100592-04-9Downstream Products

100592-04-9Relevant articles and documents

SYNTHESIS OF NEW HETEROCYCLIC PHENOLS: 8-HYDROXY-IMIDAZOPYRIDINE

Rydzkowski, R.,Blondeau, D.,Sliwa, H.

, p. 2571 - 2574 (2007/10/02)

Preparation of the unknown title compound has been achieved by condensation of 2-amino-3-hydroxy-pyridine with chloroacetaldehyde.Activation by the free phenolic hydroxyl allows preferential nitration of the pyridine ring, in marked contrast to the behavior of the related ethers which suffer electrophilic substitution on the imidazole moiety, as usual in the series.

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