102519-34-6

Basic information

• Product Name: 2,3,23-Trihydroxy-12-oleanen-28-oic acid
• Synonyms: 2,3,23-Trihydroxy-12-oleanen-28-oic acid
• CAS NO: 102519-34-6
• Molecular Formula: C₃₀H₄₈O₅
• Molecular Weight: 489
• Mol File: 102519-34-6.mol

Chemical Properties

• Boiling Point: 606.0±55.0 °C(Predicted)
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• PKA: 4.62±0.70(Predicted)
• CAS DataBase Reference: 2,3,23-Trihydroxy-12-oleanen-28-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,23-Trihydroxy-12-oleanen-28-oic acid(102519-34-6)
• EPA Substance Registry System: 2,3,23-Trihydroxy-12-oleanen-28-oic acid(102519-34-6)

Safety Data

• Hazardous Substances Data: 102519-34-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,3,23-Trihydroxy-12-oleanen-28-oic acid is used as an active pharmaceutical ingredient for its anti-inflammatory properties, aiming to alleviate inflammation-related conditions and diseases.
Used in Oncology:
In the field of oncology, 2,3,23-Trihydroxy-12-oleanen-28-oic acid is utilized as an anticancer agent, targeting various types of cancer by potentially inhibiting tumor growth and progression.
Used in Diabetes Treatment:
2,3,23-Trihydroxy-12-oleanen-28-oic acid is explored for its potential role in diabetes management, with the aim of improving glycemic control and treating complications associated with the disease.
Used in Drug Development:
2,3,23-Trihydroxy-12-oleanen-28-oic acid is also used in drug development for its bioactivity, with ongoing research focusing on optimizing its therapeutic potential and developing novel formulations to enhance its efficacy and safety profile in clinical applications.

Upstream product

• 106256-46-6 3-O-<α-L-arabinopyranosyl(1->2)-β-D-glucopyranosyl>-bayogenin 
• 118041-50-2 lobatoside C 
• 120057-47-8 undeca-acetate of medicoside J 
• 104513-86-2 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oic acid-28-O-β-D-xylopyranosyl-(1→6)-[β-D-glucopyranosyl-(1→2)]-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranoside 
• 124275-97-4 lobatoside C 
• 1189348-34-2 3-β-[(O-β-D-glucopyranosyl-(1->4)-O-[α-L-rhamnopyranosyl-(1->2)]-α-L-arabinopyranosyl)oxy]-2β,23-dihydroxyolean-12-en-28-oic acid 
• 1191300-09-0 β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-[α-L-arabinopyranosyl-(1->3)]-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 1191300-10-3 β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-[β-D-apio-D-furanosyl-(1->3)]-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 1191300-11-4 β-D-xylopyranosyl-(1->4)-[α-L-rhamnopyranosyl-(1->3)]-α-L-rhamnopyranosyl-(1->2)-[α-L-arabinopyranosyl-(1->3)]-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 1191300-12-5 β-D-xylopyranosyl-(1->4)-[α-L-rhamnopyranosyl-(1->3)]-α-L-rhamnopyranosyl-(1->2)-[α-L-arabinopyranosyl-(1->3)]-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 1191300-13-6 β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-{[β-D-apio-D-furanosyl-(1->3)]-4-O-(8-oxo-16-β-[(D-xylopyranosyl)oxy]hexadecanoyl)}-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 
• 1191300-14-7 β-D-xylopyranosyl-(1->4)-α-L-rhamnopyranosyl-(1->2)-{[β-D-apio-D-furanosyl-(1->3)]-4-O-(9-oxo-16-β-[(D-xylopyranosyl)oxy]hexadecanoyl)}-α-L-arabinopyranosyl 3-O-β-D-glucopyranosyl-2β,3β,23-trihydroxyolean-12-en-28-oate 

Downstream Products

• 106861-86-3 bayogenin triacetate 
• 22425-81-6 Methyl 2β,3β-dihydroxy-23α-hydroxymethyl-Δ¹²-oleanene-28β-carboxylate 
• 26553-62-8 olean-12-ene-2β,3β,23,28-tetraol 
• 22452-82-0 2α,3β,23-trihydroxyolean-12-en-28-oic acid methyl ester 
• 118766-24-8 3-hydroxy-2-carbonyl-23-norolean-3,12-diene-28-acid 
• 107420-72-4 2α,3β,23-triacetoxy-13-hydroxy-18α-oleanan-28-oic acid-lactone 
• 62312-05-4 2α,3β,23-trihydroxy-oleana-11,13(18)-dien-28-oic acid methyl ester 
• 142034-50-2 2α,3β,23-trihydroxy-12α-bromoolean-13,28-lactone 
• 60393-68-2 2α,3β,23-trihydroxyolean-12-en-28-oic acid triacetate 
• 89503-62-8 arjunolic bromo lactone triacetate 
• 471-59-0 Barringtogenol 
• 1382469-49-9 C₃₀H₄₆O₅ 
• 1382469-50-2 C₃₂H₄₈O₆ 

Relevant articles and documents

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A new complex triterpenoid saponin was isolated from the stem bark of Samanea saman by using chromatographic methods. Its structure was established as 3-[(2-O-β-d-glucopyranosyl-β-d-glucopyranosyl)oxy]-2,23-dihydroxy- (2β,3β,4α)-olean-12-en-28-oic acid O-β-d-glucopyranosyl-(1 → 3)-O-[O-β-d-glucopyranosyl-(1 → 4)]-O-6-deoxy-α-l- mannopyranosyl-(1 → 2)-6-O-[4-O-[(2E,6S)-2,6-dimethyl-1-oxo-2,7-octadienyl] -6-deoxy-α-l-mannopyranosyl)oxy]-β-d-glucopyranosyl ester (1). Structural elucidation was performed using detailed analyses of 1H and 13C NMR spectra including 2D NMR spectroscopic techniques and chemical conversions. The haemolytic activity of the saponin was evaluated using in vitro assays, and its adjuvant potential on the cellular immune response against ovalbumin antigen was investigated using in vivo models.

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