10347-14-5

Basic information

• Product Name: 1,2,4-Benzenetricarbonitrile
• CAS NO: 10347-14-5
• Molecular Formula: C9H3N3
• Molecular Weight: 153.143
• Mol File: 10347-14-5.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 1,2,4-Benzenetricarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Benzenetricarbonitrile(10347-14-5)
• EPA Substance Registry System: 1,2,4-Benzenetricarbonitrile(10347-14-5)

Safety Data

• Hazardous Substances Data: 10347-14-5(Hazardous Substances Data)

Usage

General Description

1,2,4-Benzenetricarbonitrile, also known as tricyanobenzene, is a colorless solid compound with the chemical formula C9H3N3. It is an aromatic compound with three cyano (CN) groups attached to a benzene ring. Tricyanobenzene is mainly used as a precursor for the synthesis of various organic compounds and polymers, and it is also used in the production of dyes and pharmaceuticals. It is a versatile chemical with industrial applications and is known for its high melting and boiling points, making it suitable for a variety of manufacturing processes. Additionally, tricyanobenzene has been investigated for its potential use in organic optoelectronic devices and as a building block for novel materials with unique properties.

Upstream product

• 74-90-8 hydrogen cyanide 
• 120-82-1 1,2,4-Trichlorobenzene 
• 120-94-5 1-Methylpyrrolidine 
• 712-74-3 1,2,4,5-tetracyanobenzene 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 22083-74-5 3-(1-methyl-pyrrolidin-2-yl)-pyridine 
• 1070-71-9 propiolonitrile 
• 557-21-1 zinc(II) cyanide 
• 21663-61-6 2,5-dichlorobenzonitrile 
• 31643-49-9 4-Nitrophthalonitrile 
• 89-40-7 4-nitrophthalimide 
• 136918-14-4 phthalimide 
• 6574-98-7 2,4-dichlorobenzylnitrile 
• 552-30-7 trimellitic Anhydride 

Downstream Products

• 63089-50-9 4-methylphthalonitrile 
• 1943-88-0 2,4-dicyanotoluene 
• 55984-93-5 2-methyl-1,4-dicyanobenzene 
• 88830-20-0 5-Methyl-1,2,4-benzenetricarbonitrile 

Relevant articles and documents

Palladium(II) phthalocyanines efficiently promote phosphine-free Sonogashira cross-coupling reaction at room temperature

Herein we report that exceptionally simple and inexpensive Pd(II) complexes of phthalocyanines efficiently catalyze direct formation of diphenylacetylenes at ambient conditions with low loading of catalyst (0.5 mol%). Results of this study demonstrate that terminal alkynes reacted mildly with p-substituted aryl bromides at room temperature under Pd and Cu-cocatalysis to give the corresponding phenylacetylenes in yields up to 98%. Also we have examined this catalyst in Sonogashira cross-coupling with aryl chlorides and it was very effective and this reaction at room temperature that there is no examples in recent articles. This protocol represents the first use of palladium phthalocyanine as homogeneous catalyst in the Pd/Cu-promoted Sonogashira reaction. The palladium(II) phthalocyanine complex is significantly more active in Sonogashira cross-coupling between aryl halides and terminal alkynes as compared with traditional catalysts because of absence of palladium black formation through agglomeration of metal particles and deactivation of catalyst.

Preparation method of aromatic nitrile compound or heteroaromatic nitrile compound

The invention discloses a preparation method of an aromatic nitrile compound or a heteroaromatic nitrile compound. The preparation method comprises: under the protection of an inert gas, in a solvent,under the actions of a nickel catalyst, a ligand, metal zinc and an additive, carrying out a reaction on a cyanation reagent and halogenated aromatic hydrocarbon or halogenated heteroaromatic hydrocarbon. According to the present invention, by using the inexpensive and easily-available nickel catalyst and the ligand, the halogenated aromatic hydrocarbon or halogenated heteroaromatic hydrocarbon,especially the chlorinated aromatic hydrocarbon or chlorinated heteroaromatic hydrocarbon with characteristics of low price, easy obtaining and low reaction activity can mildly and efficiently react with the cyanation reagent with low toxicity to prepare the aromatic nitrile compound or heteroaromatic nitrile compound; and the preparation method has advantages of simple operation, mildness, high efficiency and the like, and further has characteristics of good functional group compatibility, good universality of substrate and the like.

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.