103597-45-1

Basic information

• Product Name: Ultraviolet Absorbent UV-360
• Synonyms: 2,2'-Methylenebis[2-hydroxy-5-(1,1,3,3-tetramethylbutyl)-1,3-phenylene]bis(2H-benzotriazole);2,2'-Methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2H-benzotriazol-2-yl)phenol];2,2'-Methylenebis[4-tert-octyl-6-(2H-benzotriazole-2-yl)phenol];Methylene bisbenzotriazoryl tetramethylbutyl phenol;Bisoctrizole (200 mg);2,2'-Methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetamethylbuty)phenol];2,2-Methylenebis[3-(2H-benzotriazol-2-yl)-5-(1,1,3,3-tetramethylbutyl)phenol],99%;UV Absorber 360
• CAS NO: 103597-45-1
• Molecular Formula: C₄₁H₅₀N₆O₂
• Molecular Weight: 658.87
• EINECS: 403-800-1
• Product Categories: Polymer Additives;Polymer Science;Stabilizers;AZILECT;Phenoles and thiophenoles
• Mol File: 103597-45-1.mol

Chemical Properties

• Melting Point: 197-199 °C(lit.)
• Boiling Point: 771.6 °C at 760 mmHg
• Flash Point: >200°C
• Appearance: /
• Density: d20 1.2
• Vapor Pressure: 1.13E-24mmHg at 25°C
• Refractive Index: 1.615
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: almost transparency in THF
• PKA: 7.62±0.50(Predicted)
• Water Solubility: Insoluble < 5 ng/L at 25 °C
• Merck: 14,1294
• BRN: 11326835
• CAS DataBase Reference: Ultraviolet Absorbent UV-360(CAS DataBase Reference)
• NIST Chemistry Reference: Ultraviolet Absorbent UV-360(103597-45-1)
• EPA Substance Registry System: Ultraviolet Absorbent UV-360(103597-45-1)

Safety Data

• Statements: 36/37/38-53
• Safety Statements: 26-36/37/39-61
• WGK Germany: 1
• Hazardous Substances Data: 103597-45-1(Hazardous Substances Data)

Usage

Uses

Used in Polymer and Resin Industry:
Ultraviolet Absorbent UV-360 is used as a light stabilizer for polymers and resins. It helps to prevent the degradation of these materials by absorbing the harmful UV radiation, thereby extending their lifespan and maintaining their properties.
Used in Sunscreen Industry:
Ultraviolet Absorbent UV-360 is used as a broad-spectrum organic UV filter in sunscreens. It provides protection against both UV-A and UV-B rays, helping to prevent skin damage and reduce the risk of skin cancer.
Used in Organic Electronic Applications:
Ultraviolet Absorbent UV-360 is used as a UV filter in photo-luminescent dyes for organic electronic-based applications. It helps to enhance the performance and stability of these electronic devices by protecting them from the damaging effects of UV radiation.
Used in Skin Protection:
Ultraviolet Absorbent UV-360 is used in sunscreen formulations to protect the skin against blue light and other environmental assaults. It helps to prevent premature aging, sunburn, and other skin damage caused by exposure to harmful UV rays.

InChI:InChI=1/C41H50N6O2/c1-38(2,3)24-40(7,8)28-20-26(36(48)34(22-28)46-42-30-15-11-12-16-31(30)43-46)19-27-21-29(41(9,10)25-39(4,5)6)23-35(37(27)49)47-44-32-17-13-14-18-33(32)45-47/h11-18,20-23,48-49H,19,24-25H2,1-10H3

Upstream product

• 3147-75-9 Cyasorb UV 5411 
• 50-00-0 formaldehyd 
• 10333-53-6 bis-(dipropylamino)methane 

Relevant articles and documents

Solvent-free phase-transfer-catalysis synthesis of 2,2'-methylene-bis[4-tert-octyl-6-(2H-benzotriazolyl-2)]phenol

The invention relates to a method for synthesizing 2,2'-methylene-bis[4-tert-octyl-6-(2H-benzotriazolyl-2)]phenol (UV-360) through solvent-free phase transfer catalysis. The method comprises the procedures: adding UV-329, powdered sodium hydroxide, bis(di-n-propylamino)methane and a small amount of phase transfer catalyst into a reaction bulb which is equipped with a stirrer, a thermometer and a distillate receiving device, heating the reaction bulb to the temperature of about 120 DEG C with stirring, carrying out a reaction for 2 to 3 hours at this temperature and vacuum (100mmHg), and meanwhile, carrying out distilling-off so as to produce di-n-propyl amine; and after the reaction ends, carrying out procedures, such as toluene extraction, hydrochloric acid neutralization, crystallization and filtration, thereby obtaining the product. The synthesis method has the advantages that the reaction temperature is low, the reaction time is short, the yield and quality of the product are high, di-n-propyl amine is easy to recover, and the like.

Solvent-free synthesis of 2,2'-methylene-bis[4-tert-octyl-6-(2H-benzotriazolyl-2)]phenol

The invention discloses a method for synthesizing 2,2'-methylene-bis[4-tert-octyl-6-(2H-benzotriazolyl-2)]phenol (UV-360) through solvent-free condensation. The method comprises the procedures of firstly, carrying out condensation dehydration on di-n-propyl amine and formaldehyde or paraformaldehyde, which serve as raw materials, at the temperature of about 120 DEG C so as to synthesize di(n-propylamino)methane, and then, carrying out condensation with 2-(2'-hydroxyl-5'-tert-octylphenyl)benzotriazole at the temperature of about 160 DEG C under the catalysis of sodium hydroxide under solvent-free conditions, thereby synthesizing the UV-360. According to the method, no high-boiling solvent is used, so that problems of the existing methods are solved; and di-n-propyl amine is easy to recover and recycle, and the product quality is high.

Method for preparation of 2,2'-methylenebis[6-(2H-benzotriazole-2-yl)-4-(1,1,3,3-tetramethyl butyl)phenol]

The invention discloses a method for preparation of 2,2'-methylenebis[6-(2H-benzotriazole-2-yl)-4-(1,1,3,3-tetramethyl butyl)phenol]. The method comprises the steps: adding 2-(2-hydroxy-5-t-octyl)phenyl benzotriazole, an aromatic hydrocarbon solvent, secondary amine and paraformaldehyde into a reactor, heating up to 130-160 DEG C, carrying out a heat preservation dehydration reaction for 1-4 hours, adding a catalyst, dehydrating and heating up to 160-190 DEG C while heating, and carrying out heat preservation for 2-5 hours; and after the completion of the reaction, cooling the reaction liquid, neutralizing, carrying out alcohol precipitation, filtering, and drying to obtain UV-360. Compared with a conventional synthetic route, the yield of the product can reach more than or equal to 92%, and the maximum yield can reach more than or equal to 96%, so the production cost of the product is lower; the product has good quality, and the content of the product can reach more than or equal to 99.5%. Moreover, the operation process is simple and reliable, and the conditions are easy to control, so the method can meet demand of industrialized mass production.

COSMETIC TREATMENT METHOD USING A COMPOUND THAT CAN BE CONDENSED IN SITU AND A UV-RADIATION-FILTERING AGENT

The present invention relates to a method for the cosmetic treatment of the skin, comprising the application, to the skin: of a compound or group of compounds A capable of condensing in situ and exhibiting at least one reactive functional group FA which is free after condensation; and of a screening agent C which screens out UV radiation, comprising a reactive functional group FC capable of forming a covalent bond or a physical (ionic, hydrogen) bond by reaction with the functional group FA.

ALPHA-AMINO ACID DERIVATIVES FOR IMPROVING SOLUBILITY

The invention relates to the use of α-amino acid derivatives for improving the solubility of poorly soluble substances in water or aqueous solutions and to mixtures and preferred preparations.

Cosmetic compositions comprising photostabilized dibenzoylmethane compounds and 2-pyrrolidinone-4- carboxy esters

Photostable cosmetic compositions contain, formulated into a cosmetically acceptable vehicle, at least one UV-screening system that includes: (a) at least one dibenzoylmethane compound, and(b) at least one 2-pyrrolidinone-4-carboxy ester compound having the following formula (I): in which: R1 is a linear or branched C1-C20 alkyl radical, andR2 is a linear or branched C1-C20 alkyl radical which optionally includes a C5-C6 ring member, the phenyl radical, the benzyl radical or the phenethyl radical.

Sun protection compositions comprising semi-crystalline polymers and hollow latex particles

Topically applicable cosmetic/dermatological UV protection compositions having enhanced SPF contain at least one organic UV screening agent and/or at least one inorganic screening agent, such compositions also containing at least the following constituents (A) and (B): A) a semi-crystalline polymer which is solid at ambient temperature and has a melting point of greater than or equal to 30° C., containing a) a polymeric backbone and b) at least one crystallizable organic side chain and/or one crystallizable organic block forming part of the backbone of this said polymer, said polymer having a number-average molecular mass Mn of greater than or equal to 1,000, and B) hollow latex particles having a particle size ranging from 150 to 380 nm, formulated into a topically applicable, physiologically acceptable medium therefor.

COSMETIC OIL-IN-WATER EMULSION

A cosmetic or dermatological compositions of oil-in-water emulsion type, including, in a physiologically acceptable medium, at least gemini surfactant of formula (I): in which R1 and R3 denote, independently of one another, an alkyl radical containing from 1 to 25 carbon atoms; R2 denotes a spacer consisting of a linear or branched alkylene chain containing from 1 to 12 carbon atoms; X and Y denote, independently of one another, a group —(C2H4O)a—(C3H6O)bZ; n ranges from 1 to 10, in combination with an effective amount of at least one semi-crystalline polymer which is solid at ambient temperature and which has a melting point below 70° C., said polymer having a number-average molecular mass greater than or equal to 2000, said emulsion having a proportion of fatty phase of greater than 10% by weight relative to the total weight of the composition and including more than 40% by weight of non-volatile oil(s) relative to the weight of the fatty phase.

USE OF FLAVONOIDS

The present invention relates to the use of at least one flavonoid for odour improvement and/or odour stabilisation, and to corresponding compositions and the preparation thereof.

Flavonoids as Synergists for Enhancing the Action of Self-Tanning Substances

The invention relates to the use of at least one flavonoid having an uncharged flavan skeleton as synergist for enhancing the action of self-tanning substances, such as trioses and tetroses, in cosmetic and dermatological formulations and to corresponding novel compositions and to the preparation thereof.