10333-53-6

Basic information

• Product Name: N,N,N',N'-TETRA(N-PROPYL)METHYLENEDIAMINE
• Synonyms: n,n,n’,n’-tetrapropyl-methanediamin;N,N,N',N'-TETRA(N-PROPYL)METHYLENEDIAMINE;TETRA-N-PROPYL METHYLENEDIAMINE;N,N,N',N'-tetrapropylmethylenediamine;Bis(di-n-propylamino)methane
• CAS NO: 10333-53-6
• Molecular Formula: C₁₃H₃₀N₂
• Molecular Weight: 214.39
• EINECS: 233-726-3
• Mol File: 10333-53-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 241°Cat760mmHg
• Flash Point: 85.8°C
• Appearance: /
• Density: 0.832g/cm³
• PKA: 7.85±0.50(Predicted)
• CAS DataBase Reference: N,N,N',N'-TETRA(N-PROPYL)METHYLENEDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N,N',N'-TETRA(N-PROPYL)METHYLENEDIAMINE(10333-53-6)
• EPA Substance Registry System: N,N,N',N'-TETRA(N-PROPYL)METHYLENEDIAMINE(10333-53-6)

Safety Data

• Hazardous Substances Data: 10333-53-6(Hazardous Substances Data)

Usage

General Description

N,N,N',N'-Tetra(N-propyl)methylenediamine is a chemical compound with the formula C11H28N4. It is commonly used in chemical and pharmaceutical industries as a crosslinking agent for resins and polymers. N,N,N',N'-TETRA(N-PROPYL)METHYLENEDIAMINE plays a crucial role in the production of polymeric materials, such as polyurethane foam and epoxy resins. Additionally, it is utilized as a curing agent for certain adhesives and coatings. N,N,N',N'-Tetra(N-propyl)methylenediamine is known for its ability to improve the mechanical and thermal properties of various materials, making it a versatile and important chemical in industrial applications. However, it is important to handle this compound with caution, as it can be hazardous if not used properly.

Upstream product

• 274-09-9 Methylenedioxybenzene 
• 142-84-7 di-n-propylamine 
• 274-26-0 1,3-benzoxathiole 
• 50-00-0 formaldehyd 
• 16395-67-8 tris-(chloromethyl)amine 
• 5813-48-9 Methanesulfenyl chloride 

Downstream Products

• 103597-45-1 methylene bis-benzotriazolyl tetramethylbutylphenol 
• 1644189-19-4 2-benzylidene-N¹,N¹,N³,N³-tetrapropylpropane-1,3-diamine 
• 138370-37-3 5,5'-methylene-bis-(2-hydroxy-4-methoxybenzophenone) 
• 142-84-7 di-n-propylamine 
• 125989-56-2 3-Dipropylamino-1-(4-methyl-2-phenyl-thiazol-5-yl)-propan-1-one; hydrochloride 
• 18071-35-7 (N,N-dipropylamino)acetonitrile 

Relevant articles and documents

A General Acid-Mediated Hydroaminomethylation of Unactivated Alkenes and Alkynes

In comparison to the extensively studied metal-catalyzed hydroamination reaction, hydroaminomethylation has received significantly less attention despite its considerable potential to streamline amine synthesis. State-of-the-art protocols for hydroaminomethylation of alkenes rely largely on transition-metal catalysis, enabling this transformation only under highly designed and controlled conditions. Here we report a broadly applicable, acid-mediated approach to the hydroaminomethylation of unactivated alkenes and alkynes. This methodology employs cheap, readily available, and bench-stable reactants and affords the desired amines with excellent functional group tolerance and impeccable regioselectivity. The broad scope of this transformation, as well as mechanistic investigations and in situ domino functionalization reactions are reported.

Synthesis, characterization, and anti-amoebic screening of core-modified 5,20-bis{2-{[(alkyl)(alkyl′)amino]methyl}ferrocen-1-yl}-10,15-diphenyl-21, 23-dithiaporphyrin (=1,1″-(10,15-diphenyl-21,23-dithiaporphine-5,20-diyl) bis[2-{[(alkyl)(alkyl′)amino]methyl}ferrocene]) derivatives

The synthesis of the first bis-ferrocenyl-substituted core-modified porphyrins, 5,20-bis{2-{[(alkyl)-(alkyl′)amino]methyl}ferrocen-1-yl}-10, 15-diphenyl-21,23-dithiaporphyrin derivatives 6a - 6j, via a multistep route is reported (Schemes 1, 2, and 4). The synthesis was carried out through acid-catalyzed (BF3 ? Et2O) condensation of 1,1″- [thiophene-2,5-diylbis(hydroxymethyl)]bis[2-{[(alkyl)(alkyl′)amino]methyl} ferrocenes] 4a - 4j with 2,2′-[thiophene-2,5-diylbis(phenylmethylene)] bis[1H-pyrrole] (5b) in presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (=4,5-dichloro-3,6-dioxocyclohexa-1,4-diene-1,2-dicarbonitrile; DDQ). Characterization of the compounds was done at each step by means of various spectroscopic techniques. The final compounds were screened for in vitro anti-amoebic activity against the strain HM1:IMSS of E. histolytica (Table 2).

BIS-(DIALKYLAMINO)-METHANES AND THEIR TANNING ACTION

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